ReviewGeroScience2021
Strategies and cognitive reserve to preserve lexical production in aging.
Review in GeroScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Pooled it
- Structure-function dynamics in healthy cognitive aging: a graph signal processing approach.Brain structure & function · 2026Article
- Correlations between white matter hyperintensities, magnetic resonance imaging findings, and cognition in the oldest old: a multimodal cross-sectional study.GeroScience · 2026Article
- Preserved context sensitivity in language production: Lexical differentiation in older adults.Psychology and aging · 2026Article
- Frontal Vulnerability versus Temporal Resilience within the Core Language Network: Neuro-compensatory Mechanisms Underline Differential Language Aging Trajectories.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- MEG state dynamics of sentence generation: evidence for a compensatory segmentation mechanism in healthy aging.Frontiers in computational neuroscience · 2026Article
- High-Frequency rTMS Improves Visual Working Memory in Patients With aMCI: A Cognitive Neural Mechanism Study.CNS neuroscience & therapeutics · 2025Article
- Lifelong learning dimensions and their associations with late-life cognitive decline: moderating roles of socioeconomic status and early life education.Frontiers in psychology · 2025Article
- Lifespan oscillatory dynamics in lexical production: A population-based MEG resting-state analysis.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- When age tips the balance: A dual mechanism affecting hemispheric specialization for language.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- The validity of studying healthy aging with cognitive tests measuring different constructs.Scientific reports · 2024Article
- Exercise and Language Performance in Healthy Aging, Stroke and Neurodegenerative Conditions: a Scoping Review.Canadian geriatrics journal : CGJ · 2024Article
- Asynchronous behavioral and neurophysiological changes in word production in the adult lifespan.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Modeling the neurocognitive dynamics of language across the lifespan.Human brain mapping · 2024Article
- When Age Tips the Balance: a Dual Mechanism Affecting Hemispheric Specialization for Language.bioRxiv : the preprint server for biology · 2023Article
- Getting the brain into gear: An online study investigating cognitive reserve and word-finding abilities in healthy ageing.PloS one · 2023Article
- Mapping of Language-and-Memory Networks in Patients With Temporal Lobe Epilepsy by Using the GE2REC Protocol.Frontiers in human neuroscience · 2021Article
- Cognitive flexibility and brain network energy in healthy aging: An allostatic perspective from the SENECA model.Imaging neuroscience (Cambridge, Mass.)Article
- Naming as a window to word retrieval changes in healthy and pathological ageing: Methodological considerations.International journal of language & communication disordersReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the absence of any neuropsychiatric condition, older adults may show declining performance in several cognitive processes and among them, in retrieving and producing words, reflected in slower responses and even reduced accuracy compared to younger adults. To overcome this difficulty, healthy older adults implement compensatory strategies, which are the focus of this paper. We provide a review of mainstream findings on deficient mechanisms and possible neurocognitive strategies used by older adults to overcome the deleterious effects of age on lexical production. Moreover, we present findings on genetic and lifestyle factors that might either be protective or risk factors of cognitive impairment in advanced age. We propose that "aging-modulating factors" (AMF) can be modified, offering prevention opportunities against aging effects. Based on our review and this proposition, we introduce an integrative neurocognitive model of mechanisms and compensatory strategies for lexical production in older adults (entitled Lexical Access and Retrieval in Aging, LARA). The main hypothesis defended in LARA is that cognitive aging evolves heterogeneously and involves complementary domain-general and domain-specific mechanisms, with substantial inter-individual variability, reflected at behavioral, cognitive, and brain levels. Furthermore, we argue that the ability to compensate for the effect of cognitive aging depends on the amount of reserve specific to each individual which is, in turn, modulated by the AMF. Our conclusion is that a variety of mechanisms and compensatory strategies coexist in the same individual to oppose the effect of age. The role of reserve is pivotal for a successful coping with age-related changes and future research should continue to explore the modulating role of AMF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.