Evidence map›Paper›PMID 33970369›Full record

ArticleJournal of assisted reproduction and genetics2021

Triggering change in stimulation protocols: a matter of oocyte maturation and beyond.

Alexander M Quaas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of assisted reproduction and genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Alexander M QuaasDivision of Reproductive Endocrinology and Infertility, University of California, San Diego, San Diego, CA, USA. aquaas@health.ucsd.edu.ORCID http://orcid.org/0000-0002-9644-2115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the birth of Louise Brown, in vitro fertilization (IVF) stimulation protocols have evolved significantly. One particular area of focus has been the process of final oocyte maturation, during which the oocyte gains competence to support fertilization and early embryonic development up to implantation. The field of human assisted reproductive technology (ART) is witnessing increased utilization of GnRH agonists (GnRHa) as trigger agents, in addition to or instead of the traditionally used human chorionic gonadotropin (hCG). Future translational studies will reveal whether oocyte developmental competence, as reflected in live birth outcomes, are not only non-inferior, but also superior with the use of GnRHa as a trigger for both nuclear and cytoplasmic oocyte maturation.

Indexed as

In Vitro Oocyte Maturation TechniquesReproductive Techniques, AssistedAdultChorionic GonadotropinEmbryo ImplantationFemaleFertilization in VitroGonadotropin-Releasing HormoneHumansOocyte RetrievalOocytesOogenesisOvulation InductionPregnancyPregnancy RateChorionic GonadotropinGonadotropin-Releasing HormoneAssisted reproductive technologyGonadotropin-releasing hormone agonistHuman chorionic gonadotropinIn vitro fertilizationOocyte maturationOvulation trigger

Identifiers

PMID33970369
PMCPMC8266975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.