Evidence map›Paper›PMID 33970346›Full record

ReviewCurrent allergy and asthma reports2021

Role of Innate Immune System in Environmental Lung Diseases.

Marissa A Guttenberg, Aaron T Vose, Robert M Tighe

Open access · greenAbstract readReview
In one paragraph

Review in Current allergy and asthma reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Tissue-resident alveolar macrophages reduce ObioRxiv : the preprint server for biology · 2023
    Article
  12. Article
  13. Role of Macrophages in Air Pollution Exposure Related Asthma.International journal of molecular sciences · 2022
    Review
  14. Review
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marissa A GuttenbergDepartment of Medicine, Duke University, Durham, NC, USA.
Aaron T VoseDepartment of Medicine, Duke University, Durham, NC, USA.
Robert M TigheDepartment of Medicine, Duke University, Durham, NC, USA. robert.tighe@duke.edu.ORCID 0000-0002-3465-9861
Duke University · US

Funding

Duke University Program in Environmental HealthT32ES021432 · NIEHS · DUKE UNIVERSITY · PI Akhenaton-Andrew Dhafir Jones, Joel Newman Meyer · 2013 to 2026
$4.0M
CXCL10/CXCR3 regulation of ozone-induced epithelial permeabilityR01ES027574 · NIEHS · DUKE UNIVERSITY · PI TIGHE, ROBERT MATTHEW · 2018 to 2022
$3.1M
NIEHS NIH HHS R01 ES027574NIEHS NIH HHS T32 ES021432
6 · The paper itself

Abstract

The lung mucosa functions as a principal barrier between the body and inhaled environmental irritants and pathogens. Precise and targeted surveillance mechanisms are required at this lung-environment interface to maintain homeostasis and preserve gas exchange. This is performed by the innate immune system, a germline-encoded system that regulates initial responses to foreign irritants and pathogens. Environmental pollutants, such as particulate matter (PM), ozone (O

Indexed as

Air PollutantsLung DiseasesHumansImmunity, InnateLungOzoneParticulate MatterRespiratory MucosaAir PollutantsOzoneParticulate MatterAir pollutionAsthmaLung disease

Identifiers

PMID33970346
PMCPMC8311569
OpenAlexW3160327182

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.