Evidence map›Paper›PMID 33970324›Full record

ArticleArchives of gynecology and obstetrics2021

First proof-of-concept evaluation of the FUSION-X-US-II prototype for the performance of automated breast ultrasound in healthy volunteers.

Benedikt Schaefgen, Marija Juskic, Madeleine Hertel, Richard G Barr, Marcus Radicke, Anne Stieber, André Hennigs, Fabian Riedel, Christof Sohn, Joerg Heil and 1 more

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In one paragraph

Article in Archives of gynecology and obstetrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Benedikt SchaefgenDepartment of Gynecology and Obstetrics, University Breast Unit, Heidelberg, Germany.
Marija JuskicDepartment of Gynecology and Obstetrics, University Breast Unit, Heidelberg, Germany.
Madeleine HertelSiemens Healthcare GmbH, Forchheim, Germany.
Richard G BarrNortheastern Ohio Medical University and Southwoods Imaging, Youngstown, OH, USA.
Marcus RadickeSiemens Healthcare GmbH, Forchheim, Germany.
Anne StieberDepartment of Radiology, University Breast Unit, Heidelberg, Germany.
André HennigsDepartment of Gynecology and Obstetrics, University Breast Unit, Heidelberg, Germany.
Fabian RiedelDepartment of Gynecology and Obstetrics, University Breast Unit, Heidelberg, Germany.
Christof SohnDepartment of Gynecology and Obstetrics, University Breast Unit, Heidelberg, Germany.
Joerg HeilDepartment of Gynecology and Obstetrics, University Breast Unit, Heidelberg, Germany.
Michael GolattaDepartment of Gynecology and Obstetrics, University Breast Unit, Heidelberg, Germany. Michael.Golatta@med.uni-heidelberg.de.ORCID http://orcid.org/0000-0002-2605-0060

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe FUSION-X-US-II prototype was developed to combine 3D-automated breast ultrasound (ABUS) and digital breast tomosynthesis in a single device without decompressing the breast. We evaluated the technical function, feasibility of the examination workflow, image quality, breast tissue coverage and patient comfort of the ABUS device of the new prototype.

methodsIn this prospective feasibility study, the FUSION-X-US-II prototype was used to perform ABUS in 30 healthy volunteers without history of breast cancer. The ABUS images of the prototype were interpreted by a physician with specialization in breast diagnostics. Any detected lesions were measured and classified using BI-RADS

resultsOne hundred and six scans were performed (61 × CC, 23 × ML, 22 × MLO) in 60 breasts. Image acquisition and processing by the prototype was fast and accurate. Breast coverage by ABUS was approximately 90.8%. Sixteen breast lesions (all benign, classified as BIRADS

conclusionThe FUSION-X-US-II prototype allows a rapid ABUS scan with mostly high patient comfort. Technical developments resulted in an improvement of quality and coverage compared to previous prototype versions. The results are encouraging for a test of the prototype in a clinical setting in combination with tomosynthesis.

Indexed as

AdultBreastBreast NeoplasmsDiagnosis, Computer-AssistedFeasibility StudiesFemaleHealthy VolunteersHumansMammographyMiddle AgedMultimodal ImagingProof of Concept StudyProspective StudiesUltrasonography, MammaryAutomated breast ultrasoundBreast cancerDiagnosticsDigital breast tomosynthesisMultimodal imaging

Identifiers

PMID33970324
PMCPMC8277634

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.