SynthesisClinical oral investigations2021
Vital pulp therapy in carious pulp-exposed permanent teeth: an umbrella review.
Synthesis in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- The effectiveness of partial pulpotomy compared with full pulpotomy in managing deep caries in vital permanent teeth with a diagnosis of non-traumatic pulpitis.International endodontic journal · 2025Pooled it
- Pooled it
- Comparison of bioactive material failure rates in vital pulp treatment of permanent matured teeth - a systematic review and network meta-analysis.Scientific reports · 2024Pooled it
- Clinical Evaluation of Three Direct Pulp Capping Materials in Caries-Induced Pulpitis of Mature Permanent Teeth: A Randomized Controlled Trial.Clinical and experimental dental research · 2026Trial
- Clinical and radiographic evaluation of Er: YAG laser-assisted direct pulp capping in permanent teeth with carious exposure.Lasers in medical science · 2025Trial
- Full pulpotomy versus root canal therapy in mature teeth with irreversible pulpitis: a randomized controlled trial.BMC oral health · 2024Trial
- Randomized clinical trial of pulpotomy using a premixed injectable calcium silicate cement on mature permanent teeth with reversible pulpitis.Scientific reports · 2024Trial
- Outcomes of root canal therapy or full pulpotomy using two endodontic biomaterials in mature permanent teeth: a randomized controlled trial.Clinical oral investigations · 2022Trial
- Mineral Trioxide AggregateIranian endodontic journal · 2022Trial
- Zinc-containing ionic liquid combined with carboxymethyl chitosan for vital pulp therapy in mature permanent teeth with carious pulp exposure.BMC oral health · 2026Article
- The Shear Bond Strength Between Calcium Silicate-Based Biomaterials and Glass Ionomer Restorative Materials: An In Vitro Comparative Study.Journal of functional biomaterials · 2026Article
- Fracture Resistance of Mineral Trioxide Aggregate- and Biodentine-Pulpotomized teeth with Different Restorative Techniques: An in vitro Study.Journal of dentistry (Shiraz, Iran) · 2026Article
- Garlic as a novel therapeutic agent for the management of pulp infections: a systematic review.Odontology · 2026Review
- Application of the Er:YAG laser in pulpotomy for mature permanent teeth with pulpitis: An animal study.PloS one · 2026Article
- The effect of different treatment methods on apical closure and treatment success in immature permanent first molars with reversible pulpitis.BMC oral health · 2025Article
- Irisin-Loaded Cerium-Containing Mesoporous Bioactive Glass for Effective Immunomodulation and Odontogenesis of Dental Pulp Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Concentrated growth factor scaffold-based pulpotomy of permanent molars with symptomatic irreversible pulpitis.Restorative dentistry & endodontics · 2025Article
- Expert consensus on pulpotomy in the management of mature permanent teeth with pulpitis.International journal of oral science · 2025Review
- Biological evaluation of solutions from bioglass, bioglass modified with cobalt, and calcium hydroxide.Brazilian oral research · 2025Article
- Knowledge and Attitude Toward Vital Pulp Therapy Among Dental Practitioners in Jordan: A Questionnaire-Based Survey.International journal of dentistry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThere has been increasing evidence indicating rather high success rates of vital pulp therapies. This umbrella review aimed to provide an overview of existing systematic reviews regarding the outcomes of vital pulp therapy, specifically direct pulp capping, partial pulpotomy and full pulpotomy, in carious pulp-exposed permanent human teeth. MATERIALS AND
methodsThe specific PICO questions were as follows: Population - permanent human teeth with carious pulp exposure; Intervention - direct pulp capping with pulp capping materials; Comparators - partial pulpotomy and full pulpotomy; Outcomes - success rate and prognostic factors. PubMed, Ovid and Cochrane databases were searched in conjunction with hand searching. Grey literature was searched too. Study selection, data extraction and study appraisal were performed independently by two authors. A consensus was reached through discussion when disagreements arose.
resultsSix articles fulfilled the inclusion criteria. Higher and more predictable success rates of ≥ 2 years were observed for partial pulpotomy and full pulpotomy in carious pulp-exposed permanent human teeth as compared to direct pulp capping. Possible prognostic factors (pre-operative pulp status, pulp capping material and apex closure) yielded conflicting results. Restorative material, periapical status at baseline, final irrigation solution, age and study type did not seem to affect the treatment outcome.
conclusionsVital pulp therapy is a reliable treatment option for permanent teeth with carious pulp exposure. However, more high-quality studies are required to corroborate this finding. CLINICAL RELEVANCE: Vital pulp therapy could be considered as an alternative for root canal treatment for carious pulp-exposed permanent teeth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.