ArticleDer Unfallchirurg2021
[Infections of the spine : Pyogenic spondylodiscitis and implant-associated vertebral osteomyelitis].
Article in Der Unfallchirurg, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 13 citations in OpenAlex.
- Comparison of Hospital Mortality and Risk Factors in Conservative and Surgical Treatment of Pyogenic Vertebral Osteomyelitis: A Nationwide Analysis of 49,951 Cases in Germany.Global spine journal · 2026Article
- The Modified Spinal Instability Spondylodiscitis Score (mSISS): Adaptation and Validation of a Novel Classification System for Spinal Instability in Spondylodiscitis.Global spine journal · 2026Article
- Systemic immune responses in patients with spine surgery related infections.Frontiers in immunology · 2026Article
- Case Report: Interim success in treating pyogenic spondylitis caused by Staphylococcus epidermidis using UBE technology: a rare case.Frontiers in surgery · 2026Article
- Suppurative Spondylitis Misdiagnosed as Endplate Inflammation: A Rare Case Report.Clinical case reports · 2025Article
- [Antibiotics (Basel, Switzerland) · 2024Article
- Anterior Column Reconstruction of Destructive Vertebral Osteomyelitis at the Thoracolumbar Spine with an Expandable Vertebral Body Replacement Implant: A Retrospective, Monocentric Radiological Cohort Analysis of 24 Cases.Journal of clinical medicine · 2024Article
- Midterm survival and risk factor analysis in patients with pyogenic vertebral osteomyelitis: a retrospective study of 155 cases.Frontiers in surgery · 2024Article
- Risk Factors for the In-Hospital Mortality in Pyogenic Vertebral Osteomyelitis: A Cross-Sectional Study on 9753 Patients.Journal of clinical medicine · 2023Article
- The Epidemiology of Spondylodiscitis in Germany: A Descriptive Report of Incidence Rates, Pathogens, In-Hospital Mortality, and Hospital Stays between 2010 and 2020.Journal of clinical medicine · 2023Article
- Long-term patient-related quality of life outcomes and ICD-10 symptom rating (ISR) of patients with pyogenic vertebral osteomyelitis: What is the psychological impact of this life-threatening disease?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- [Infections of the spinal cord and adjacent structures].Der Nervenarzt · 2023Review
- [Current practice of empiric antibiotic treatment for spondylodiscitis].Orthopadie (Heidelberg, Germany) · 2022Article
- A Novel Construct to Treat Destructive Osteomyelitis of the Lumbar Spine in a Patient With Pre-existing Paraplegia.Cureus · 2022Article
- Georg schmorl prize of the German spine society (DWG) 2021: Spinal Instability Spondylodiscitis Score (SISS)-a novel classification system for spinal instability in spontaneous spondylodiscitis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Article
- Thoracic spondylodiscitis secondary toJournal of spine surgery (Hong Kong) · 2022Article
- Is There a Difference in Clinical Features, Microbiological Epidemiology and Effective Empiric Antimicrobial Therapy Comparing Healthcare-Associated and Community-Acquired Vertebral Osteomyelitis?Antibiotics (Basel, Switzerland) · 2021Article
- [Use of video-assisted thoracoscopy in dorsoventral stabilization of osteodestructive pyogenic spondylodiscitis of the thoracic spine].Der Unfallchirurg · 2021Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pyogenic (unspecific) spondylodiscitis and implant-associated vertebral osteomyelitis (IAVO) are important diseases with the risk of neurological and septic complications. An early diagnosis is essential in which magnetic resonance imaging (MRI), histopathology and microbiological identification of the pathogen play key roles. The goals of conservative treatment in uncomplicated spondylodiscitis are antibiotic infection control and pain management. In the case of sepsis, neurological deficits, segmental instability or epidural abscesses surgical treatment of the infection with stabilization of the spine should be considered. In IAVO the formation of a mature biofilm represents the transition from acute to chronic infection. Acute infections can be treated by extensive debridement in combination with biofilm-active antibiotic treatment while retaining the implant. In chronic infections implant removal or exchange in combination with several weeks of antibiotic treatment is often necessary.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.