ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2022
Incidence and risk factors for symptomatic venous thromboembolism following anterior cruciate ligament reconstruction.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Thromboprophylaxis After ACL Reconstruction: Controversies and Future Challenges.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Two-year outcomes following concomitant ACL and extra-articular ligament reconstruction: a nationwide analysis of over 5,000 patients.Archives of orthopaedic and trauma surgery · 2026Article
- Limited indication of postoperative anticoagulation based on age reduces the incidence of deep venous thrombosis after anterior cruciate ligament reconstruction: A retrospective study.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2026Article
- Impact of Diabetes Mellitus on Complications and Revision Risk After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis.Orthopaedic journal of sports medicine · 2026Review
- Attention-Deficit/Hyperactivity Disorder in Anterior Cruciate Ligament Reconstruction Patients ≤25 Years of Age: A National Database Study of Prevalence and Outcomes.Ochsner journal · 2026Article
- Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study.SICOT-J · 2025Article
- The incidence of venous thromboembolism in patients undergoing arthroscopic anterior cruciate ligament repair: A proposed thromboprophylaxis regimen.Qatar medical journal · 2025Article
- Article
- Aspirin is as effective as low molecular weight heparins in preventing symptomatic venous thromboembolism following arthroscopic anterior cruciate ligament reconstruction.BMC musculoskeletal disorders · 2024Article
- Adverse Events After Isolated Posterior Cruciate Ligament Reconstruction: A National Database Study.Orthopaedic journal of sports medicine · 2024Article
- A comparative analysis of suture-augmented and standard hamstring autograft single-bundle ACL reconstruction outcomes: short-term functional benefits without long-term impact.BMC musculoskeletal disorders · 2023Article
- Anterior cruciate ligament tear increases the risk of venous thromboembolism: a population-based cohort study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Postoperative Anterior Cruciate Ligament Reconstruction Quadricep and Patella Tendon Rupture, Infection, and Lysis of Adhesions Decreased Despite Changing Graft Trends Over the Past Decade.Arthroscopy, sports medicine, and rehabilitation · 2022Article
- Does anterior cruciate ligament reconstruction increase venous thromboembolism risk compared with knee meniscectomy under arthroscopy?BMC musculoskeletal disorders · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the incidence of symptomatic venous thromboembolism (VTE) following anterior cruciate ligament (ACL) reconstruction using a large national database and to identify corresponding independent risk factors.
methodsThe Humana administrative claims database was reviewed for patients undergoing ACL reconstruction from 2007 to 2017. Patient demographics, medical comorbidities, as well as concurrent procedures were recorded. Postoperative incidence of VTE was measured by identifying symptomatic deep vein thrombosis (DVT) and pulmonary embolism (PE) at 30 days, 90 days, and 1 year postoperatively. Univariate analysis and binary logistic regression were performed to determine independent risk factors for VTE following surgery.
resultsA total of 11,977 patients were included in the study. The incidence of VTE was 1.01% (n = 120) and 1.22% (n = 146) at 30 and 90 days, respectively. Analysis of VTE events within the first postoperative year revealed that 69.6% and 84.3% of VTEs occurred within 30 and 90 days of surgery, respectively. Logistic regression identified age ≥ 45 (odds ratio [OR] = 1.88; 95% confidence interval [CI] 1.32-2.68; p < 0.001), inpatient surgery (OR = 2.07; 95% CI 1.01-4.24; p = 0.045), COPD (OR = 1.51; 95% CI 1.02-2.24; p = 0.041), and tobacco use (OR = 1.75; 95% CI 1.17-2.62; p = 0.007), as well as concurrent PCL reconstruction (OR = 3.85; 95% CI 1.71-8.67; p = 0.001), meniscal transplant (OR = 17.68; 95% CI 3.63-85.97; p < 0.001) or osteochondral allograft (OR = 15.73; 95% CI 1.79-138.43; p = 0.013) as independent risk factors for VTE after ACL reconstruction.
conclusionsThe incidence of symptomatic postoperative VTE is low following ACL reconstruction, with the majority of cases occurring within 90 days of surgery. Risk factors include age ≥ 45, inpatient surgery, COPD, tobacco use and concurrent PCL reconstruction, meniscal transplant or osteochondral allograft. LEVEL OF EVIDENCE: III.
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