ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2021
Identification of local atrial conduction heterogeneities using high-density conduction velocity estimation.
Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 39 citations in OpenAlex.
- Artificial intelligence-guided pulsed field ablation for persistent atrial fibrillation: automated peak frequency mapping predicts termination sites and durable rhythm control.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Utility of slow conduction velocity area guided ablation in patients with persistent atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Epicardial muscle bundles in persistent atrial fibrillation: from overlooked bystanders to arrhythmogenic modulators.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Review
- Rapid calibration of atrial electrophysiology models using Gaussian process emulators in the ensemble Kalman filter.Scientific reports · 2026Article
- Men and women's hearts don't beat the same: Epicardial mapping of Bachmann's bundle.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025Article
- Left atrial deceleration outperforms regional conduction velocity in predicting arrhythmia recurrence following atrial fibrillation ablation.Heart rhythm O2 · 2025Article
- Sex differences in atrial potential morphology.International journal of cardiology. Heart & vasculature · 2025Article
- The impact of atrial voltage and conduction velocity phenotypes on atrial fibrillation recurrence.Frontiers in cardiovascular medicine · 2024Article
- Electrophysiological Markers ofTransplant international : official journal of the European Society for Organ Transplantation · 2024Article
- How sex affects the sinus rhythm heartbeat.International journal of cardiology. Heart & vasculature · 2023Article
- Electroanatomical Conduction Characteristics of Pig Myocardial Tissue Derived from High-Density Mapping.Journal of clinical medicine · 2023Article
- 25 years of basic and translational science in EP Europace: novel insights into arrhythmia mechanisms and therapeutic strategies.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Review
- Differences in atrial substrate localization using late gadolinium enhancement-magnetic resonance imaging, electrogram voltage, and conduction velocity: a cohort study using a consistent anatomical reference frame in patients with persistent atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Atrial extrasystoles enhance low-voltage fractionation electrograms in patients with atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Mapping-guided atrial lead placement determines optimal conduction across Bachmann's bundle: a rationale for patient-tailored pacing therapy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Does conduction heterogeneity determine the supervulnerable period after atrial fibrillation?Medical & biological engineering & computing · 2023Article
- Premature atrial contractions promote local directional heterogeneities in conduction velocity vectors.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Atrial conduction velocity mapping: clinical tools, algorithms and approaches for understanding the arrhythmogenic substrate.Medical & biological engineering & computing · 2022Review
- Active force generation contributes to the complexity of spontaneous activity and to the response to stretch of murine cardiomyocyte cultures.The Journal of physiology · 2022Article
- Clinical Relevance of Sinus Rhythm Mapping to Quantify Electropathology Related to Atrial Fibrillation.Arrhythmia & electrophysiology review · 2022Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsAccurate determination of intra-atrial conduction velocity (CV) is essential to identify arrhythmogenic areas. The most optimal, commonly used, estimation methodology to measure conduction heterogeneity, including finite differences (FiD), polynomial surface fitting (PSF), and a novel technique using discrete velocity vectors (DVV), has not been determined. We aim (i) to identify the most suitable methodology to unravel local areas of conduction heterogeneities using high-density CV estimation techniques, (ii) to quantify intra-atrial differences in CV, and (iii) to localize areas of CV slowing associated with paroxysmal atrial fibrillation (PAF). METHODS AND
resultsIntra-operative epicardial mapping (>5000 sites, interelectrode distances 2 mm) of the right and left atrium and Bachmann's bundle (BB) was performed during sinus rhythm (SR) in 412 patients with or without PAF. The median atrial CV estimated using the DVV, PSF, and FiD techniques was 90.0 (62.4-116.8), 92.0 (70.6-123.2), and 89.4 (62.5-126.5) cm/s, respectively. The largest difference in CV estimates was found between PSF and DVV which was caused by smaller CV magnitudes detected only by the DVV technique. Using DVV, a lower CV at BB was found in PAF patients compared with those without atrial fibrillation (AF) [79.1 (72.2-91.2) vs. 88.3 (79.3-97.2) cm/s; P < 0.001].
conclusionsAreas of local conduction heterogeneities were most accurately identified using the DVV technique, whereas PSF and FiD techniques smoothen wavefront propagation thereby masking local areas of conduction slowing. Comparing patients with and without AF, slower wavefront propagation during SR was found at BB in PAF patients, indicating structural remodelling.
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