Evidence map›Paper›PMID 33970129›Full record

ArticleJournal of visualized experiments : JoVE2021

Psychophysical Tracking Method to Assess Taste Detection Thresholds in Children, Adolescents, and Adults: The Taste Detection Threshold (TDT) Test.

Paule V Joseph, Julie A Mennella, Beverly J Cowart, M Yanina Pepino

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Paule V JosephNational Institute of Alcohol Abuse and Alcoholism, Section of Sensory Science and Metabolism.
Julie A MennellaMonell Chemical Senses Center.
Beverly J CowartMonell Chemical Senses Center.
M Yanina PepinoDepartment of Food Science and Human Nutrition, University of Illinois at Urbana Champaign; ypepino@illinois.edu.
Monell Chemical Senses Center · USNational Institute on Alcohol Abuse and Alcoholism · USUniversity of Illinois Urbana-Champaign · US

Funding

Taste of medicines for children: genetic variation and medical adherenceR01DC011287 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI LOWENTHAL, ELIZABETH DAWN, MENNELLA, JULIA ANNE · 2011 to 2022
$4.3M
Sensory Science and Metabolism; Molecular and Neuronal Mechanisms ZIAAA000136 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI JOSEPH, PAULE · 2021 to 2025
$3.2M
Downshifting Sweet Preference and Added Sugar Intake During Snacking Among Young Children: A Randomized Controlled TrialR01DC016616 · NIDCD · TEMPLE UNIV OF THE COMMONWEALTH · PI FISHER, JENNIFER ORLET, MENNELLA, JULIA ANNE · 2018 to 2022
$3.1M
Mechanisms Underlying Individual Variations of Taste and Smell in ObesityZIAAA000135 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI JOSEPH, PAULE · 2021 to 2025
$1.2M
Intramural NIH HHS ZIA AA000135NIDCD NIH HHS R01 DC011287NIDCD NIH HHS R01 DC016616
6 · The paper itself

Abstract

This paper describes a two-alternative, forced-choice, staircase, tracking procedure, called the Taste Detection Threshold (TDT) test, that provides a reliable measure of sweet, salty, and umami taste detection thresholds from childhood to adulthood. Advantages of the method include procedures that are identical for children and adults, thus allowing the determination of age-related and individual differences in taste perception, if any, and tasks that can be completed in a relatively short time frame, do not rely on continuous attention or require memorization, control for subjective response biases, and minimize the impact of language development. After a 1 hour fast, participants are presented with pairs of solutions; in each pair, one solution is water, and the other solution contains varying concentrations of the tastant. Using a whole-mouth tasting method, participants taste each solution (without swallowing and with rinsing between tastings) and then point to the solution with a taste or that tastes different from water. The concentration of the stimulus in the subsequent pair increases after a single incorrect response and decreases after two consecutive correct responses. A reversal occurs when the concentration sequence changes direction. The task is deemed completed after the occurrence of four reversals, provided there are a maximum of two dilution steps between two successive reversals, and the series of reversals do not form an ascending pattern. These additional criteria ensure greater reliability in outcomes. The TDT is then calculated as the geometric mean of the concentrations of the four reversals. This method has real-world relevance as it provides information on a dimension of taste perception that is independent of hedonics, and that can change with aging and certain disease states, making it a valuable psychophysical test.

Indexed as

AdolescentAdultChildFemaleHumansMalePsychophysicsResearch DesignTasteYoung Adult

Identifiers

PMID33970129
PMCPMC8560331
OpenAlexW3157231235

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.