ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2021
Clinical outcomes of the proximal optimisation technique (POT) in bifurcation stenting.
Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Sirolimus-coated versus paclitaxel-coated balloons for bifurcated coronary lesions in the side branch: the SPACIOUS trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025Trial
- Middle East Bifurcation Club Consensus Document on Percutaneous Revascularization of Bifurcation Lesions in Association with the National Heart CenterSaudi medical journal · 2026Article
- Coronary Bifurcation PCI-Part I: Fundamentals.Journal of cardiovascular development and disease · 2025Review
- Routine intracoronary imaging-guided left main coronary intervention.Scientific reports · 2025Article
- Assessment of fractal ratio of vessel diameters in coronary bifurcation lesions by angiography and intravascular ultrasound.Cardiovascular intervention and therapeutics · 2025Article
- Expanding our understanding on stent expansion.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Article
- Letter: Cardiovascular outcomes after 2-stent or stepwise provisional techniques for coronary bifurcation lesions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Article
- Review of Progress in Interventional Therapy for Coronary Bifurcation Lesions.Reviews in cardiovascular medicine · 2024Review
- Review of Techniques for Protecting Side Branch from Occlusion during Provisional Stenting in Coronary Bifurcation Lesions.Reviews in cardiovascular medicine · 2023Review
- Impact of coronary bifurcation angle on stent malapposition in a randomized comparison between proximal optimization technique followed by side branch dilatation and kissing balloon inflation.International journal of cardiology. Heart & vasculature · 2023Article
- Stepwise provisional versus systematic culotte for stenting of true coronary bifurcation lesions: five-year follow-up of the multicentre randomised EBC TWO Trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023Article
- Clinical Characteristics and Outcomes following Percutaneous Coronary Intervention in Unprotected Left Main Disease: A Single-Center Study.Diagnostics (Basel, Switzerland) · 2023Article
- Must absolutely accurate balloon position be achieved during POT? MoreFrontiers in cardiovascular medicine · 2023Article
- An Approach to Non-left Main Bifurcation Lesions: A Contemporary Review.US cardiology · 2023Review
- Recent Evidence on Advances in PCI Treatment for Left Main Coronary Artery Disease.Reviews in cardiovascular medicine · 2022Review
- Percutaneous coronary intervention of bifurcation lesions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Article
- Stent Fractures: New Insights into an Old Issue.Journal of clinical medicine · 2022Article
- Post-stenting optimisation techniques in bifurcation percutaneous coronary interventions: much remains to be explored.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Article
- Towards a common pathway for the treatment of left main disease: contemporary evidence and future directions: Left main disease treatment.AsiaIntervention · 2021Review
- Standardisation of techniques for bifurcation stenting optimisation: the journey continues.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOptimal deployment of coronary stents in a bifurcation lesion remains a matter of debate.
aimsWe sought to capture the daily practice of bifurcation stenting by means of a worldwide registry and to investigate how post-implantation deployment techniques influence clinical outcomes.
methodsData from the e-ULTIMASTER registry were used to perform an analysis of 4,395 patients undergoing percutaneous coronary intervention for bifurcation lesions. Inverse probability of treatment weights (IPTW) propensity score methodology was used to adjust for any baseline differences. The primary outcome of interest was target lesion failure (TLF) at one year (follow-up rate 96.2%).
resultsThe global one-year TLF rate was low (5.1%). The proximal optimisation technique (POT) was used in 33.9% of cases and was associated with a reduction in the adjusted TLF rate (4.0% [95% confidence interval: 3.0-5.1%] vs 6.0% [5.1-6.9%], p<0.01) due to a reduction of all components of this composite endpoint, except for cardiac death. Stent thrombosis was also positively impacted (0.4% [0.04-0.7%] vs 1.3% [0.8-1.7%], p<0.01). POT benefit was uniform across subgroups. Conversely, the use of the kissing balloon technique (36.5%) did not influence the adjusted TLF rate.
conclusionsDespite a low one-year failure rate in this large bifurcation stenting cohort, POT was associated with a further reduction in the event rate and a uniform benefit across subgroups, suggesting systematic use of this deployment technique regardless of the bifurcation anatomy and stenting technique.
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