Evidence map›Paper›PMID 33969828›Full record

ArticleJournal of biosciences2021

MRTF-A regulates Ca

Chen Liang, Yao Xu, Zhen Peng, Ying Luo, Tongcun Zhang

Abstract read
PubMed
In one paragraph

Article in Journal of biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chen LiangCollege of Life Science and Health, Wuhan University of Science and Technology, Wuhan 430065, China.
Yao Xu
Zhen Peng
Ying Luo
Tongcun Zhang
Wuhan University of Science and Technology · CNMinzu University of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene therapy is considered a potential treatment for Duchenne muscular dystrophy (DMD). Researchers have been working on this for many years to find effective therapeutic targets. Here, we found that MRTF-A (myocardin-related transcription factor A) could activate the transcription of L-type Ca

Indexed as

AnimalsCalciumCalcium Channels, L-TypeCell LineChlorocebus aethiopsCOS CellsDisease Models, AnimalGene Expression RegulationGenes, ReporterHumansIon TransportLuciferasesMiceMice, Inbred C57BLMice, Inbred mdxMuscular Dystrophy, DuchenneCACNA1S protein, mouseCalciumCalcium Channels, L-TypeLuciferasesMrtfa protein, mouseTrans-Activators

Identifiers

PMID33969828
OpenAlexW3159797307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.