Evidence map›Paper›PMID 33969463›Full record

ArticleAnnals of surgical oncology2021

Minimally Invasive Versus Open Pancreatectomy for Right-Sided and Left-Sided G1/G2 Nonfunctioning Pancreatic Neuroendocrine Tumors: A Multicenter Matched Analysis with an Inverse Probability of Treatment-Weighting Method.

Ho Kyoung Hwang, Ki Byung Song, Minsu Park, Wooil Kwon, Jin-Young Jang, Jin Seok Heo, Dong Wook Choi, Chang Moo Kang, Joon Seong Park, Tae Ho Hong and 12 more

Open access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 1 country.

Ho Kyoung Hwang *Department of Hepatobiliary and Pancreatic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Ki Byung Song *Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea.
Minsu ParkDepartment of Statistics, Keimyung University, Daegu, Korea.
Wooil KwonDepartment of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Jin-Young JangDepartment of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Jin Seok HeoDivision of Hepatobiliary-Pancreatic Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Dong Wook ChoiDivision of Hepatobiliary-Pancreatic Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Chang Moo KangDepartment of Hepatobiliary and Pancreatic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Joon Seong ParkDepartment of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Tae Ho HongDepartment of Hepatobiliary and Pancreas Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Chol Kyoon ChoDepartment of Surgery, Chonnam National University Hwasun Hospital, Hwasun, Jeollanamdo, Korea.
Keun Soo AhnDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Keimyung University Dongsan Hospital, Daegu, Korea.
Huisong LeeDepartment of Surgery, Ewha Womans University College of Medicine, Seoul, Korea.
Seung Eun LeeDepartment of Surgery, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, Korea.
Chi-Young JeongDepartment of Surgery, Gyeongsang National University School of Medicine, Jinju, Korea.
Young Hoon RohDepartment of Surgery, Dong-A University College of Medicine, Busan, Korea.
Hee Joon KimDepartment of Surgery, Chonnam National University Hospital, Gwangju, Korea.
Dae Wook HwangDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea.
Song Cheol KimDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea.
Ho-Seong HanDepartment of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea.
Yoo-Seok YoonDepartment of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea. yoonys@snubh.org.
Korean Pancreas Surgery Club
Asan Medical Center · KRSeoul National University Bundang Hospital · KRYonsei University · KRKeimyung University · KRSamsung Medical Center · KRChonnam National University Hospital · KRChung-Ang University Hospital · KREwha Womans University · KRSeoul National University · KRChonnam National University Hwasun Hospital · KRDong-A University · KRGyeongsang National University · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited evidence exists for the safety and oncologic efficacy of minimally invasive surgery (MIS) for nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs) according to tumor location. This study aimed to compare the surgical outcomes of MIS and open surgery (OS) for right- or left-sided NF-PNETs.

methodsThe study collected data on patients who underwent surgical resection (pancreatoduodenectomy, distal/total/central pancreatectomy, duodenum-preserving pancreas head resection, or enucleation) of a localized NF-PNET between January 2000 and July 2017 at 14 institutions. The inverse probability of treatment-weighting method with propensity scores was used for analysis.

resultsThe study enrolled 859 patients: 478 OS and 381 MIS patients. A matched analysis by tumor location showed no differences in resection margin, intraoperative blood loss, or complications between MIS and OS. However, MIS was associated with a longer operation time for right-sided tumors (393.3 vs 316.7 min; P < 0.001) and a shorter postoperative hospital stay for left-sided tumors (8.9 vs 12.9 days; P < 0.01). The MIS group was associated with significantly higher survival rates than the OS group for right- and left-sided tumors, but survival did not differ for the patients divided by tumor grade and location. Multivariable analysis showed that MIS did not affect survival for any tumor location.

conclusionThe short-term outcomes offered by MIS were comparable with those of OS except for a longer operation time for right-sided NF-PNETs. The oncologic outcomes were not compromised by MIS regardless of tumor location or grade. These findings suggest that MIS can be performed safely for selected patients with localized NF-PNETs.

Indexed as

Neuroendocrine TumorsPancreatic NeoplasmsHumansMinimally Invasive Surgical ProceduresPancreatectomyPancreaticoduodenectomyPropensity ScoreRetrospective StudiesTreatment Outcome

Identifiers

PMID33969463
OpenAlexW3163281122

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.