Evidence map›Paper›PMID 33969457›Full record

ArticleJournal of clinical monitoring and computing2022

Development of an automated closed-loop β-blocker delivery system to stably reduce myocardial oxygen consumption without inducing circulatory collapse in a canine heart failure model: a proof of concept study.

Takuya Nishikawa, Kazunori Uemura, Yohsuke Hayama, Toru Kawada, Keita Saku, Masaru Sugimachi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical monitoring and computing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Takuya NishikawaDepartment of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center Research Institute, Kishibe-Shinmachi 6-1, Suita, Japan. nishikawa.takuya75@ncvc.go.jp.ORCID 0000-0002-4951-7831
Kazunori UemuraDepartment of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center Research Institute, Kishibe-Shinmachi 6-1, Suita, Japan.ORCID 0000-0003-2900-4702
Yohsuke HayamaDepartment of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center Research Institute, Kishibe-Shinmachi 6-1, Suita, Japan.ORCID 0000-0003-3836-2333
Toru KawadaDepartment of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center Research Institute, Kishibe-Shinmachi 6-1, Suita, Japan.ORCID 0000-0002-4429-1802
Keita SakuDepartment of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center Research Institute, Kishibe-Shinmachi 6-1, Suita, Japan.ORCID 0000-0001-9404-7069
Masaru SugimachiDepartment of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center Research Institute, Kishibe-Shinmachi 6-1, Suita, Japan.
National Cerebral and Cardiovascular Center · JP

Funding

Japan Society for the Promotion of Science 18K12126Japan Society for the Promotion of Science 19K20690National Cerebral and Cardiovascular Center 31-6-4
6 · The paper itself

Abstract

Beta-blockers are well known to reduce myocardial oxygen consumption (MVO

Indexed as

Heart FailureShockAdrenergic beta-AntagonistsAnimalsCardiac OutputDogsHemodynamicsHumansOxygen ConsumptionProof of Concept StudyAdrenergic beta-AntagonistsAutomated drug deliveryBeta-blockerClosed-loop controlHemodynamics

Identifiers

PMID33969457
PMCPMC9162998
OpenAlexW3163204386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.