Evidence map›Paper›PMID 33969267›Full record

ReviewAdvanced composites and hybrid materials2021

Modification strategies to improve the membrane hemocompatibility in extracorporeal membrane oxygenator (ECMO).

Ting He, Jinhui He, Zhaohui Wang, Zhaoliang Cui

Open access · bronzeAbstract readReview
In one paragraph

Review in Advanced composites and hybrid materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
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  9. Characterization of anisotropic pore structure and dense selective layer of capillary membranes for long-term ECMO by cross-sectional ion-milling method.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Article
  10. Article
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  12. 3D porous structure imaging of membranes for medical devices using scanning probe microscopy and electron microscopy: from membrane science points of view.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2024
    Review
  13. Article
  14. Reducing hydrophobic drug adsorption in an in-vitro extracorporeal membrane oxygenation model.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ting HeState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing Tech University, 210009 Nanjing, China.
Jinhui HeNational Engineering Research Center for Special Separation Membrane, Nanjing Tech University, 210009 Nanjing, China.
Zhaohui WangJiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University, 210009 Nanjing, China.
Zhaoliang CuiState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing Tech University, 210009 Nanjing, China.
Nanjing Tech University · CNThe Synergetic Innovation Center for Advanced Materials · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractSince extracorporeal membrane oxygenator (ECMO) has been utilized to save countless lives by providing continuous extracorporeal breathing and circulation to patients with severe cardiopulmonary failure. In particular, it has played an important role during the COVID-19 epidemic. One of the important composites of ECMO is membrane oxygenator, and the core composite of the membrane oxygenator is hollow fiber membrane, which is not only a place for blood oxygenation, but also is a barrier between the blood and gas side. However, the formation of blood clots in the oxygenator is a key problem in the using process. According to the study of the mechanism of thrombosis generation, it was found that improving the hemocompatibility is an efficient approach to reduce thrombus formation by modifying the surface of materials. In this review, the corresponding modification methods (surface property regulation, anticoagulant grafting, and bio-interface design) of hollow fiber membranes in ECMO are classified and discussed, and then, the research status and development prospects are summarized. GRAPHICAL ABSTRACT:

Indexed as

ECMOHemocompatibilityHollow fiber membraneSurface modification

Identifiers

PMID33969267
PMCPMC8091652
OpenAlexW3158024254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.