Evidence map›Paper›PMID 33969108›Full record

ArticleWorld journal of clinical cases2021

Association between scrub typhus encephalitis and diffusion tensor tractography detection of Papez circuit injury: A case report.

Hyeok Gyu Kwon, Jeong-Hee Yang, Jee-Hyun Kwon, Dongseok Yang

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hyeok Gyu KwonDepartment of Physical Therapy, College of Health Science, Eulji University, Sanseong-daero 13135, Gyeonggi-do, South Korea.
Jeong-Hee YangDepartment of Plastic Surgery, Biomedical Research Institute, Seoul National University Hospital, Jongno-gu 03080, Seoul, South Korea.
Jee-Hyun KwonDepartment of Neurology, University of Ulsan College of Medicine, Ulsan University Hospital, Dong-gu 44033, Ulsan, South Korea.
Dongseok YangDepartment of Physical Medicine and Rehabilitation, University of Ulsan College of Medicine, Ulsan University Hospital, Dong-gu 44033, Ulsan, South Korea. fnew11@gmail.com.
Ulsan University Hospital · KREulji University · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is difficult to restore the cognitive functions of patients with impaired cognition caused by brain injury. Diffusion tensor imaging can visualize the integrity of neural tracts in the white matter (WM) three-dimensionally. It is unclear whether encephalitis following scrub typhus damages the WM. For the first time, we aimed to report diffusion tensor tractography (DTT) findings in a chronic patient with cognitive impairment following scrub typhus encephalitis, which revealed injury to the Papez circuit of the WM. CASE SUMMARY: A 70-year-old male patient was affected by encephalitis caused by scrub typhus that occurred 23 years ago. He had poor cognition and his clinical examination findings were as follows: Mini-Mental Status Examination score, 14; and handgrip strength (right/left, kg), 32.3/31.3. DTT revealed serious injuries of the left thalamocingulate tract and right mammillothalamic tract in the Papez circuit, and a partial injury of the anterior part of the fornix.

conclusionUsing DTT, we found a relationship between cognitive impairment and the integrity of the Papez circuit following scrub typhus.

Indexed as

Case reportCognitionDiffusion tensor imagingEncephalitisPapez circuitScrub typhusWhite matter

Identifiers

PMID33969108
PMCPMC8080737
OpenAlexW3157084862

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.