Evidence map›Paper›PMID 33968820›Full record

ArticleAutopsy & case reports2021

Isolated cerebral mucormycosis masquerading as a tumor in an immunocompetent patient.

Smita Chandra, Shubhi Sharma, Ruchir Vats, Sanjeev Pandey

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Autopsy & case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Smita ChandraSwami Rama Himalayan University, Himalayan Institute of Medical Sciences, Department of Pathology, Dehradun, Uttarakhand, India.ORCID 0000-0002-0652-4708
Shubhi SharmaSwami Rama Himalayan University, Himalayan Institute of Medical Sciences, Department of Pathology, Dehradun, Uttarakhand, India.ORCID 0000-0002-6692-560X
Ruchir VatsSwami Rama Himalayan University, Himalayan Institute of Medical Sciences, Department of Neurosurgery, Dehradun, Uttarakhand, India.ORCID 0000-0002-5516-0584
Sanjeev PandeySwami Rama Himalayan University, Himalayan Institute of Medical Sciences, Department of Neurosurgery, Dehradun, Uttarakhand, India.ORCID 0000-0002-9157-7264
Swami Rama Himalayan University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucormycosis is an opportunistic fungal disease that commonly presents as cutaneous or rhinocerebral infections associated with immunocompromised states. It may exceptionally present as isolated involvement of the brain with a varied clinical presentation, which may be difficult to diagnose early, leading to increased mortality. Herein, we report the case of a 42-year-old immunocompetent female with left-sided limb weakness and a history of recurrent vomiting and headache for the last two years. Clinically, glioma was suspected, but histopathological examination revealed a few broad aseptate fungal hyphae. As no other organ was involved, the diagnosis of isolated cerebral mucormycosis was rendered. Reporting this case, we show an unusual presentation of a central nervous system mucormycosis masquerading a tumor in an immunocompetent patient. The case also highlights the importance of a careful histopathological examination to avoid missing the presence of occasional fungal hyphae. Ideally, recognition of fungal hyphae in the brain, during intraoperative consultation, can prompt brain tissue culture for definitive diagnosis and early empirical antifungal therapy, which may prove life-saving.

Indexed as

Cerebral CortexImmunocompromised HostMucormycosis

Identifiers

PMID33968820
PMCPMC8020582
OpenAlexW3127765959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.