Evidence map›Paper›PMID 33968777›Full record

ArticleFrontiers in oncology2021

The Role of Dectin-1 Signaling in Altering Tumor Immune Microenvironment in the Context of Aging.

Natarajan Bhaskaran, Sangeetha Jayaraman, Cheriese Quigley, Prerna Mamileti, Mahmoud Ghannoum, Aaron Weinberg, Jason Thuener, Quintin Pan, Pushpa Pandiyan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

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  6. Multidrug-ResistantThe Malaysian journal of medical sciences : MJMS · 2025
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  14. Sweet Immune Checkpoint Targets to Enhance T Cell Therapy.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Natarajan BhaskaranDepartment of Biological Sciences, School of Dental Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.
Sangeetha JayaramanDepartment of Biological Sciences, School of Dental Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.
Cheriese QuigleyDepartment of Biological Sciences, School of Dental Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.
Prerna MamiletiDepartment of Biological Sciences, School of Dental Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.
Mahmoud GhannoumDepartment of Pathology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.
Aaron WeinbergDepartment of Biological Sciences, School of Dental Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.
Jason ThuenerOtolaryngology-Head and Neck surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.
Quintin PanDepartment of Pathology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.
Pushpa PandiyanDepartment of Biological Sciences, School of Dental Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.
University Hospitals of Cleveland · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increased accumulation of immune-dysfunction-associated CD4

Indexed as

agingCandidaFoxp3IL-1βoral cancerTregTreg17tumorigenesis

Identifiers

PMID33968777
PMCPMC8100664
OpenAlexW3155701761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.