ArticleGland surgery2021
Expression and significance of estrogen receptor and progesterone receptor in endometrial tissue of patients with intrauterine adhesions.
Article in Gland surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- A novel intrauterine estrogen-releasing system for preventing the postoperative recurrence of intrauterine adhesion: a multicenter randomized controlled study.BMC medicine · 2024Trial
- Long-term effects of hysteroscopic adhesiolysis on postoperative pregnancy rates and fertility outcomes in patients with intrauterine adhesions.American journal of translational research · 2024Article
- Decoding the endometrial niche of Asherman's Syndrome at single-cell resolution.Nature communications · 2023Article
- A comparison of special intrauterine balloons and intrauterine contraceptive devices in the treatment of intrauterine adhesions.Archives of gynecology and obstetrics · 2023Article
- Estradiol and intrauterine device treatment for moderate and severe intrauterine adhesions after transcervical resection.BMC women's health · 2022Article
- Comparison of the Reproductive Outcome Between 2 and 4 mg Daily Doses of Estradiol After Hysteroscopic Adhesiolysis: A Propensity Score Matching Analysis-Retrospective Cohort Study.Frontiers in endocrinology · 2022Article
- Visual Analysis of Uterine Adhesion Research Based on CiteSpace: Bibliometric Analysis From 2006 to 2021.Frontiers in reproductive health · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur study aims to analyze the expression and significance of estrogen receptor (ER) and progesterone receptor (PR) in endometrial tissues of patients with intrauterine adhesion (IUA).
methodsFifty-four patients with IUAs examined in our hospital from January 2017 to January 2019 were selected as the research object (observation group), 54 healthy women who had physical examinations during the same period were selected as the control group, and the immunohistochemical EnVision was used. Two-step and real-time fluorescent quantitative PCR methods were used to detect the expression levels of ER and PR in the endometrial tissues of the two groups of subjects.
resultsThe immunohistochemical test results showed that ER's expression level in the observation group was significantly higher than that in the control group, and the difference between the two groups was statistically significant (P<0.05). The difference in PR expression levels between the two groups was insignificant (P<0.05). Real-time fluorescent quantitative PCR results showed ER and PR's expression levels in the observation group were significantly higher than those in the control group, and the difference between the two groups was statistically significant (P<0.05).
conclusionsAfter IUA can detect ER and PR expression, we can formulate a personalized hormone treatment plan to improve the clinical treatment effect.
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Registered trials
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