ArticlePlastic and reconstructive surgery. Global open2021
Closed Incisional Negative Pressure Therapy Significantly Reduces Early Wound Dehiscence after Reduction Mammaplasty.
Article in Plastic and reconstructive surgery. Global open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06265558 (Prevention of Postoperative Complications by Negative Pressure Therapy After Complex Breast Cancer Surgery), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention of Postoperative Complications by Negative Pressure Therapy After Complex Breast Cancer Surgery: a Prospective Randomized Controlled Trial
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical and economic impact of incisional negative pressure wound therapy in breast surgery: meta-analysis.The British journal of surgery · 2026Pooled it
- Effectiveness of prophylactic application of negative pressure wound therapy in stopping surgical site wound problems for closed incisions in breast cancer surgery: A meta-analysis.International wound journal · 2023Pooled it
- Postoperative Mechanomodulation Decreases T-Junction Dehiscence After Reduction Mammaplasty: Early Scar Analysis From a Randomized Controlled Trial.Aesthetic surgery journal · 2023Trial
- The Use of Negative Pressure Wound Therapy for Breast Surgeries: A Systematic Review and Meta-Analysis.Plastic surgery (Oakville, Ont.) · 2026Review
- Environmental, Nutritional, and Therapeutic Factors That Affect Surgical Wound Healing: A Narrative Review of Experimental Findings From the Last 5 Years.Health science reports · 2026Article
- Article
- Efficacy of Vacuum-assisted Wound Closure in Improving Healing in Breast Surgery Patients: AReview.Plastic and reconstructive surgery. Global open · 2025Article
- Salvage of Nipple-areolar Complex Venous Congestion Following Reduction Mammaplasty with Full-coverage Incisional Negative Pressure Wound Therapy.Journal of plastic and reconstructive surgery · 2025Article
- Injective hydrogel loaded with liposomes-encapsulated MY-1 promotes wound healing and increases tensile strength by accelerating fibroblast migration via the PI3K/AKT-Rac1 signaling pathway.Journal of nanobiotechnology · 2024Article
- Randomized Controlled Trial to Assess Negative Pressure Wound Therapy versus Standard-of-care Dressings in Breast Surgery: A Pilot Study.Plastic and reconstructive surgery. Global open · 2024Article
- Article
- Closed Incision Negative Pressure Therapy versus Standard of Care in Reduction of Surgical Site Complications: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2023Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClosed incisional negative pressure therapy (ciNPT) has been shown to improve surgical outcomes. Functional reduction mammaplasty has a wound dehiscence rate of 25% and higher in most series, requiring extra care and delayed secondary healing. We aimed to determine if shifting from standard care dressings to ciNPT reduced early dehiscence after breast reduction.
methodsThis multisurgeon retrospective study compared consecutive patients undergoing primary breast reduction dressed with ciNPT to similar patients with standard dressing materials. Perioperative management was otherwise unchanged. Early dehiscence was defined as incisional disruption requiring wound care within the first 30 postoperative days. Statistical analyses were performed using t-test and Fisher exact test.
resultsWe analyzed 79 patients with 158 breasts (114 standard and 44 ciNPT). Both groups were similar. Mean ages were 35 and 34 years; body mass index, 28.5 and 27.4 kg/m
conclusionApplication of ciNPT markedly decreased early dehiscence requiring wound care, compared to using standard dressings, in otherwise similarly risk-stratified breast reduction patients.
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Registered trials
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