Evidence map›Paper›PMID 33968515›Full record

ArticleCureus2021

Rapid Development of Clinically Symptomatic Radiation Recall Pneumonitis Immediately Following COVID-19 Vaccination.

Cole R Steber, Janardhana Ponnatapura, Ryan T Hughes, Michael K Farris

Abstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. In Regard to Soyfer et al.International journal of radiation oncology, biology, physics · 2022
    Article
  8. Article
  9. Cutaneous findings following COVID-19 vaccination: review of world literature and own experience.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Radiation Recall Phenomenon Following COVID-19 Vaccination.International journal of radiation oncology, biology, physics · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cole R SteberRadiation Oncology, Wake Forest School of Medicine, Winston-Salem, USA.
Janardhana PonnatapuraRadiology, Wake Forest School of Medicine, Winston-Salem, USA.
Ryan T HughesRadiation Oncology, Wake Forest School of Medicine, Winston-Salem, USA.
Michael K FarrisRadiation Oncology, Wake Forest School of Medicine, Winston-Salem, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this report, we present the case of a 66-year-old man who received local consolidation radiotherapy to the right lung and mediastinum for oligometastatic non-small cell lung cancer (NSCLC) following partial response to upfront chemoimmunotherapy. He continued with maintenance immunotherapy and was asymptomatic for eight months after completing radiation therapy. He then developed symptoms consistent with pneumonitis within three to five days of his first administration of the coronavirus disease 2019 (COVID-19) vaccine injection. He reported that these symptoms significantly intensified within three to five days of receiving his second dose of the vaccine. The clinical time frame and radiographic evidence raised suspicion for radiation recall pneumonitis (RRP). Patients undergoing maintenance immunotherapy after prior irradiation may be at increased risk of this phenomenon that may be triggered by the administration of the COVID-19 vaccine.

Indexed as

covid-19covid-19 vaccineimmunotherapynon-small cell lung carcinoma (nsclc)nsclcoligometastaticradiation recall pneumonitis

Identifiers

PMID33968515
PMCPMC8098628

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.