Evidence map›Paper›PMID 33968073›Full record

ArticleFrontiers in immunology2021

Capturing T Lymphocytes' Dynamic Interactions With Human Neural Cells Using Time-Lapse Microscopy.

Florent Lemaître, Ana Carmena Moratalla, Negar Farzam-Kia, Yves Carpentier Solorio, Olivier Tastet, Aurélie Cleret-Buhot, Jean Victor Guimond, Elie Haddad, Nathalie Arbour

Open access · goldAbstract readComparative StudyVideo-Audio Media
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Florent LemaîtreDepartment of Neurosciences, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Ana Carmena MoratallaDepartment of Neurosciences, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Negar Farzam-KiaDepartment of Neurosciences, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Yves Carpentier SolorioDepartment of Neurosciences, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Olivier TastetCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada.
Aurélie Cleret-BuhotCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada.
Jean Victor GuimondCentre Local de Services Communautaires des Faubourgs, Centre Intégré Universitaire en Santé et Services Sociaux du Centre-Sud-de-l'Ile-de-Montréal, Montréal, QC, Canada.
Elie HaddadCentre de Recherche du Centre Hospitalier Universitaire Sainte-Justine (CHU Sainte-Justine), Department of Microbiology, Infectious Diseases, and Immunology and Department of Pediatrics, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Nathalie ArbourDepartment of Neurosciences, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Centre Hospitalier de l’Université de Montréal · CAUniversité de Montréal · CACentre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To fully perform their functions, T lymphocytes migrate within organs' parenchyma and interact with local cells. Infiltration of T lymphocytes within the central nervous system (CNS) is associated with numerous neurodegenerative disorders. Nevertheless, how these immune cells communicate and respond to neural cells remains unresolved. To investigate the behavior of T lymphocytes that reach the CNS, we have established an

Indexed as

Cell CommunicationMicroscopy, VideoTime-Lapse ImagingAdultAstrocytesCD8-Positive T-LymphocytesCell MovementCells, CulturedCoculture TechniquesFemaleHistocompatibility Antigens Class IHumansInflammationInterleukin-1betaMaleMiddle AgedHistocompatibility Antigens Class IIL1B protein, humanInterleukin-1betaastrocytesinflammationlive imagingMHC class Ineurons

Identifiers

PMID33968073
PMCPMC8100528
OpenAlexW3156811282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.