Evidence map›Paper›PMID 33968068›Full record

ArticleFrontiers in immunology2021

The Synergistic Effects of Polysaccharides and Ginsenosides From American Ginseng (

Rongrong Zhou, Dan He, Jing Xie, Qingyijun Zhou, Hongliang Zeng, Hongmei Li, Luqi Huang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 173 citations in OpenAlex.

  1. Effect of AG1Frontiers in nutrition · 2026
    Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Microorganisms · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Polysaccharide fromFoods (Basel, Switzerland) · 2026
    Article
  11. Review
  12. Review
  13. Review
  14. Immunomodulatory effects ofFrontiers in immunology · 2026
    Article
  15. Article
  16. ButyrylatedActa pharmaceutica Sinica. B · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Targeting Metabolism: Innovative Therapies for MASLD Unveiled.International journal of molecular sciences · 2025
    Review

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rongrong ZhouSchool of Pharmacy, Changchun University of Chinese Medicine, Changchun, China.
Dan HeHunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Jing XieHunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Qingyijun ZhouHunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Hongliang ZengHunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Hongmei LiInsitute of Chinese Materia, China Academy of Chinese Medical Sciences, Beijing, China.
Luqi HuangNational Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Hunan University of Traditional Chinese Medicine · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclophosphamide (CTX), used in cancer chemotherapy, a high dose of which would cause immunosuppressive effect and intestinal mucosa damage. American ginseng (

Indexed as

AnimalsBacteriaCyclophosphamideDrug Therapy, CombinationFecesGastrointestinal MicrobiomeGinsenosidesImmune System DiseasesImmunomodulationImmunosuppressive AgentsIntestinal MucosaMetabolomicsMicePanaxPolysaccharidesCyclophosphamideGinsenosidesImmunosuppressive AgentsPolysaccharidesAmerican ginsengfecal metabolitesgut barrier functiongut microbiotaimmunostimulant

Identifiers

PMID33968068
PMCPMC8100215
OpenAlexW3157119452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.