Evidence map›Paper›PMID 33968018›Full record

ReviewFrontiers in immunology2021

The Role of CD4

Kiyoshi Hirahara, Kota Kokubo, Ami Aoki, Masahiro Kiuchi, Toshinori Nakayama

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 47 citations in OpenAlex.

  1. Trial
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  10. Pregnancy-acquired memory CD4Nature communications · 2025
    Article
  11. Article
  12. The role of mTOR activation in steroid-resistant asthma: insights from particulate matter-induced mouse model and patient studies.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  13. Review
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kiyoshi HiraharaDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kota KokuboDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Ami AokiDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Masahiro KiuchiDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Toshinori NakayamaDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Chiba University · JPJapan Agency for Medical Research and Development · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Memory T cells are crucial for both local and systemic protection against pathogens over a long period of time. Three major subsets of memory T cells; effector memory T (T

Indexed as

Immunity, MucosalImmunologic MemoryCD4-Positive T-LymphocytesCell PlasticityDisease SusceptibilityEpigenesis, GeneticGene Expression RegulationHost-Pathogen InteractionsHumansMucous MembraneOrgan SpecificityT-Lymphocyte SubsetsAspergillus fumigatusATAC-seqCD4+ resident memory T cellsinducible bronchus-associated lymphoid tissue (iBALT)lung fibrosispathogenic T cell

Identifiers

PMID33968018
PMCPMC8097179
OpenAlexW3153998637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.