Evidence map›Paper›PMID 33968014›Full record

ReviewFrontiers in immunology2021

Reprogramming Immune Cells for Enhanced Cancer Immunotherapy: Targets and Strategies.

Yan Dong, Zhuo Wan, Xiaotong Gao, Guodong Yang, Li Liu

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
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  6. [Preparation of Trop2-Targeted CAR-T Cells Based on Nanobodies and Their Antitumor Effects Against Non-Small Cell Lung Cancer].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
  7. Article
  8. Review
  9. Review
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  11. Article
  12. Article
  13. Review
  14. The roles of inflammasomes in cancer.Frontiers in immunology · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Targeting of the tumor immune microenvironment by metformin.Journal of cell communication and signaling · 2022
    Review
  19. Irradiation immunity interactions.Journal of medical imaging and radiation oncology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yan DongDepartment of Hematology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Zhuo WanDepartment of Hematology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Xiaotong GaoDepartment of Hematology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Guodong YangDepartment of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China.
Li LiuDepartment of Hematology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the leading causes of death and a major public health problem all over the world. Immunotherapy is becoming a revolutionary clinical management for various cancer types. Restoration of aberrant immune surveillance on cancers has achieved markable progress in the past years by either

Indexed as

ImmunomodulationAnimalsCellular ReprogrammingGenetic EngineeringHumansImmunotherapyImmunotherapy, AdoptiveKiller Cells, NaturalLymphocytes, Tumor-InfiltratingNeoplasmsReceptors, Antigen, T-CellReceptors, Chimeric AntigenT-LymphocytesTumor-Associated MacrophagesTumor MicroenvironmentReceptors, Antigen, T-CellReceptors, Chimeric Antigencancer immune therapycell engineeringimmune cellsstrategiestargets

Identifiers

PMID33968014
PMCPMC8097044

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.