ArticleFrontiers in microbiology2021
High Potential for Biomass-Degrading Enzymes Revealed by Hot Spring Metagenomics.
Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Diverse thermophilic anaerobes from Indian hot springs show potential for bioenergy production from lignocellulosic biomass.World journal of microbiology & biotechnology · 2026Article
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- Biotechnological Applications of Archaea.Progress in molecular and subcellular biology · 2026Review
- Spatiotemporal Profiling of Starch-Degrading Enzymes in Nong-Flavor Daqu: Molecular Markers for Quantitative Quality Evaluation.Foods (Basel, Switzerland) · 2025Article
- Structural and functional insights into extreme thermal stability and activity of two GH12 domains of a multidomain glycosidase from a hyperthermophilic euryarchaeon.The FEBS journal · 2025Article
- Microbial Enrichments Contribute to Characterization Of Desert Tortoise Gut Microbiota.Microbial ecology · 2025Article
- Distribution of early-branching Cyanobacteriia and the potential habitats that gave rise to the earliest oxygenic phototrophs.mSphere · 2025Article
- Impact of moisture on microbial decomposition phenotypes and enzyme dynamics.The ISME journal · 2025Article
- Phylogenetic diversity and community structure ofFrontiers in microbiology · 2025Article
- Genome-guided isolation of the hyperthermophilic aerobe Fervidibacter sacchari reveals conserved polysaccharide metabolism in the Armatimonadota.Nature communications · 2024Article
- NGS-Based Metagenomics Depicting Taxonomic and Functional Insights into North-Western Himalayan Hot Springs.Indian journal of microbiology · 2024Article
- Article
- Comparative genomic analysis of Planctomycetota potential for polysaccharide degradation identifies biotechnologically relevant microbes.BMC genomics · 2024Article
- Integrating multi-platform assembly to recover MAGs from hot spring biofilms: insights into microbial diversity, biofilm formation, and carbohydrate degradation.Environmental microbiome · 2024Article
- Extremophiles in a changing world.Extremophiles : life under extreme conditions · 2024Review
- An improved protocol for metagenomic DNA isolation from low microbial biomass alkaline hot-spring sediments and soil samples.3 Biotech · 2024Article
- Functional and sequence-based metagenomics to uncover carbohydrate-degrading enzymes from composting samples.Applied microbiology and biotechnology · 2023Article
- Engineering the Metabolic Landscape of Microorganisms for Lignocellulosic Conversion.Microorganisms · 2023Review
- Biodegradation of plastics: mining of plastic-degrading microorganisms and enzymes using metagenomics approaches.Journal of microbiology (Seoul, Korea) · 2022Review
- Novel bacterial taxa in a minimal lignocellulolytic consortium and their potential for lignin and plastics transformation.ISME communications · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enzyme stability and activity at elevated temperatures are important aspects in biotechnological industries, such as the conversion of plant biomass into biofuels. In order to reduce the costs and increase the efficiency of biomass conversion, better enzymatic processing must be developed. Hot springs represent a treasure trove of underexplored microbiological and protein chemistry diversity. Herein, we conduct an exploratory study into the diversity of hot spring biomass-degrading potential. We describe the taxonomic diversity and carbohydrate active enzyme (CAZyme) coding potential in 71 publicly available metagenomic datasets from 58 globally distributed terrestrial geothermal features. Through taxonomic profiling, we detected a wide diversity of microbes unique to varying temperature and pH ranges. Biomass-degrading enzyme potential included all five classes of CAZymes and we described the presence or absence of genes encoding 19 glycosyl hydrolases hypothesized to be involved with cellulose, hemicellulose, and oligosaccharide degradation. Our results highlight hot springs as a promising system for the further discovery and development of thermo-stable biomass-degrading enzymes that can be applied toward generation of renewable biofuels. This study lays a foundation for future research to further investigate the functional diversity of hot spring biomass-degrading enzymes and their potential utility in biotechnological processing.
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