ReviewFrontiers in endocrinology2021
Cyclic Cushing's Syndrome - A Diagnostic Challenge.
Review in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 20 citations in OpenAlex.
- Episodic hypercortisolemia-mediated periods of worsening hyperglycemia in cyclic Cushing syndrome.JCEM case reports · 2026Article
- Cyclic Cushing syndrome as a clinical enigma and diagnostic dilemma in advanced endocrinology.Journal of endocrinological investigation · 2026Review
- Article
- A challenging diagnosis of pediatric (cyclic) Cushing disease: the decisive role of hair cortisol.JCEM case reports · 2026Article
- Biases of large language models in diagnosing Cushing's syndrome.World journal of methodology · 2026Review
- Case Report: Continuous block-and-replace strategy with osilodrostat in a patient with cyclic Cushing's syndrome.Frontiers in endocrinology · 2026Article
- Three Cases of Ectopic, Cyclic Cushing Syndrome: A New Square Wave Variant.JCEM case reports · 2025Article
- A Rare Cyclic Cushing Syndrome Mystery Illustrates Diagnostic Principles.JCEM case reports · 2024Article
- Advancements in Cortisol Detection: From Conventional Methods to Next-Generation Technologies for Enhanced Hormone Monitoring.ACS sensors · 2024Review
- Germline PRKACA amplification-associated primary pigmented nodular adrenocortical disease: a case report and literature review.Archives of endocrinology and metabolism · 2023Review
- [Cyclic Cushing's syndrome: difficulties of diagnostic search and choice of treatment tactics. A clinical case].Problemy endokrinologii · 2023Article
- The expression of glucocorticoid and mineralocorticoid receptors in pituitary tumors causing Cushing's disease and silent corticotroph tumors.Frontiers in endocrinology · 2023Article
- Cortisol as an Independent Predictor of Unfavorable Outcomes in Hospitalized COVID-19 Patients.Biomedicines · 2022Article
- Hair cortisol in polycystic ovary syndrome.Scientific reports · 2022Article
- The promising role of risk scoring system for Cushing syndrome: Time to reconsider current screening recommendations.Frontiers in endocrinology · 2022Review
- Grand Challenge in Adrenal Endocrinology: Is the Legacy of the Past a Challenge for the Future of Precision Medicine?Frontiers in endocrinology · 2021Article
- Old Problem, New Concerns: Hypercortisolemia in the Time of COVID-19.Frontiers in endocrinology · 2021Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyclic Cushing's syndrome (also known as intermittent or periodic) is a disease characterized by periods of transient hypercortisolemia shifting into periods of normo- and/or hypocortisolemia. Diagnosis of cyclic Cushing's syndrome is based on at least three periods of confirmed hypercortisolemia interspersed by two periods of normocortisolemia. Cyclic Cushing's syndrome is one of the greatest challenges in modern endocrinology due to its diverse clinical picture, unpredictable duration and frequency of phases, and various etiologies. We discuss a diagnostic algorithm for periodic hypercortisolemia with special regard to hair cortisol analysis and desmopressin stimulation test which both seem to be helpful in finding the correct answer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.