Evidence map›Paper›PMID 33967822›Full record

ArticleFrontiers in physiology2021

Medullary Noradrenergic Neurons Mediate Hemodynamic Responses to Osmotic and Volume Challenges.

Stefanne Madalena Marques, Lara Marques Naves, Talita de Melo E Silva, Keilah Valéria Naves Cavalcante, Juliana Milan Alves, Marcos Luiz Ferreira-Neto, Carlos Henrique de Castro, Andre Henrique Freiria-Oliveira, James Oluwagbamigbe Fajemiroye, Rodrigo Mello Gomes and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Stefanne Madalena MarquesDepartment of Physiology, Biological Sciences Institute, Federal University of Goiás, Goiânia, Brazil.
Lara Marques NavesDepartment of Physiology, Biological Sciences Institute, Federal University of Goiás, Goiânia, Brazil.
Talita de Melo E SilvaDepartment of Physiology and Biophysics, Institute of Biomedical Science, University of São Paulo, São Paulo, Brazil.
Keilah Valéria Naves CavalcanteDepartment of Physiology, Biological Sciences Institute, Federal University of Goiás, Goiânia, Brazil.
Juliana Milan AlvesDepartment of Physiology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Marcos Luiz Ferreira-NetoDepartment of Physiology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Carlos Henrique de CastroDepartment of Physiology, Biological Sciences Institute, Federal University of Goiás, Goiânia, Brazil.
Andre Henrique Freiria-OliveiraDepartment of Physiology, Biological Sciences Institute, Federal University of Goiás, Goiânia, Brazil.
James Oluwagbamigbe FajemiroyeDepartment of Physiology, Biological Sciences Institute, Federal University of Goiás, Goiânia, Brazil.
Rodrigo Mello GomesDepartment of Physiology, Biological Sciences Institute, Federal University of Goiás, Goiânia, Brazil.
Eduardo ColombariDepartment of Physiology and Pathology, School of Dentistry, São Paulo State University (UNESP), Araraquara, Brazil.
Carlos Henrique XavierDepartment of Physiology, Biological Sciences Institute, Federal University of Goiás, Goiânia, Brazil.
Gustavo Rodrigues PedrinoDepartment of Physiology, Biological Sciences Institute, Federal University of Goiás, Goiânia, Brazil.
Universidade Federal de Goiás · BRUniversidade Federal de Uberlândia · BRUniversidade de São Paulo · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite being involved in homeostatic control and hydro-electrolyte balance, the contribution of medullary (A1 and A2) noradrenergic neurons to the hypertonic saline infusion (HSI)-induced cardiovascular response after hypotensive hemorrhage (HH) remains to be clarified. Hence, the present study sought to determine the role of noradrenergic neurons in HSI-induced hemodynamic recovery in male Wistar rats (290-320 g) with HH. Medullary catecholaminergic neurons were lesioned by nanoinjection of antidopamine-β-hydroxylase-saporin (0.105 ng·nl

Indexed as

blood pressurecentral nervous systemhypertonic salinelesionresuscitation

Identifiers

PMID33967822
PMCPMC8103169
OpenAlexW3158776337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.