Evidence map›Paper›PMID 33967143›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Cartilage-hair Hypoplasia Complicated with Liver Cirrhosis Due to Chronic Intrahepatic Cholestasis.

Taro Kogami, Haruki Uojima, Takasuke Ebato, Yuki Bando, Akiyoshi Hoshino, Makoto Saegusa, Makoto Ohbu, Shuichiro Iwasaki, Naohisa Wada, Kousuke Kubota and 5 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Taro KogamiDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Haruki UojimaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Takasuke EbatoDepartment of Pediatrics, Kitasato University School of Medicine, Japan.
Yuki BandoDepartment of Pediatrics, Kitasato University School of Medicine, Japan.
Akiyoshi HoshinoDepartment of Pathology, Kitasato University School of Medicine, Japan.
Makoto SaegusaDepartment of Pathology, Kitasato University School of Medicine, Japan.
Makoto OhbuDepartment of Pathology, Kitasato Institute Hospital, Japan.
Shuichiro IwasakiDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Naohisa WadaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Kousuke KubotaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Yoshiaki TanakaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Hisashi HidakaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Takahide NakazawaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Akitaka ShibuyaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Wasaburo KoizumiDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Kitasato University · JPKitasato Institute Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a rare case of cartilage-hair hypoplasia (CHH) complicated with liver cirrhosis. A 20-year-old Japanese man with CHH was found incidentally to have liver cirrhosis and an esophageal varix. This patient had been treated for infections due to immunodeficiency since early childhood. He ultimately died of liver failure at 31 years of age. An autopsy revealed an abnormality of the interlobular bile ducts and intrahepatic cholestasis. Liver cirrhosis was thought to have been caused by chronic intrahepatic cholestasis due to biliary duct hypoplasia and changes in the intestinal microbiome. Therefore, CHH may cause biliary cirrhosis due to multiple effects.

Indexed as

Cholestasis, IntrahepaticHirschsprung DiseasePrimary Immunodeficiency DiseasesAdultFatal OutcomeHairHumansLiver CirrhosisMaleOsteochondrodysplasiasYoung Adultagammaglobulinemiabiliary hypoplasiacartilage-hair hypoplasiachronic intrahepatic cholestasisliver cirrhosis

Identifiers

PMID33967143
PMCPMC8627820
OpenAlexW3162504301

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.