Evidence map›Paper›PMID 33966595›Full record

Observational studyRenal failure2021

Extracellular water/total body water ratio as predictor of mortality in hemodialysis patients.

Rosa Pérez-Morales, Javier Donate-Correa, Ernesto Martín-Núñez, Nayra Pérez-Delgado, Carla Ferri, Aurora López-Montes, Alejandro Jiménez-Sosa, Juan Francisco Navarro-González

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Renal failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 34 citations in OpenAlex.

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  7. Evaluation of skeletal muscle indicators following allogeneic hematopoietic stem cell transplantation: verification of skeletal muscle mass adjustment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  17. Use of bioimpedance in prevention of sarcopenia in the elderly.Central European journal of public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rosa Pérez-MoralesNephrology Department, Hospital Universitario Nuestra Señora de Candelaria (HUNSC), Santa Cruz de Tenerife, Spain.
Javier Donate-CorreaResearch Unit, HUNSC, Santa Cruz de Tenerife, Spain.
Ernesto Martín-NúñezResearch Unit, HUNSC, Santa Cruz de Tenerife, Spain.
Nayra Pérez-DelgadoClinical Analysis Service, HUNSC, Santa Cruz de Tenerife, Spain.
Carla FerriResearch Unit, HUNSC, Santa Cruz de Tenerife, Spain.
Aurora López-MontesNephrology Department, Complejo Hospitalario Universitario de Albacete, Albacete, Spain.
Alejandro Jiménez-SosaResearch Unit, Hospital Universitario de Canarias, La Laguna, Spain.
Juan Francisco Navarro-GonzálezNephrology Department, Hospital Universitario Nuestra Señora de Candelaria (HUNSC), Santa Cruz de Tenerife, Spain.
Hospital Universitario Nuestra Señora de Candelaria · ESComplejo Hospitalario Universitario de Albacete · ESHospital Universitario de Canarias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOverhydration is a predictor of mortality in hemodialysis (HD) patients. Bioimpedance spectroscopy (BIS) is used to determine the body composition. Extracellular Water/Total Body Water (ECW/TBW) ratio has been proposed to predict mortality.

methodsMulticenter, prospective, observational, proof-of-concept study to estimate the impact of ECW/TBW in global and cardiovascular mortality and the relationship with cardiovascular biomarkers. The study included 60 patients (mean age, 71.8 ± 11.4 years; mean time on HD, 52.3 ± 30.8 months) with a median follow-up of 30.5 months (IQ range, 17.2-34 months).

resultsPost-dialysis ECW/TBW was directly associated with NT-proBNP and cTnT. During the study 28 patients died, most of them (43%) due to cardiovascular events. Compared to the survivors, these subjects had a higher post-dialysis ECW/TBW ratio (

conclusionsThe post-dialysis ECW/TBW ratio measured by BIS can be a predictor of all-cause and cardiovascular mortality.

Indexed as

Electric ImpedanceRenal DialysisAgedAged, 80 and overBody WaterCardiovascular DiseasesCause of DeathExtracellular SpaceFemaleHumansLogistic ModelsMaleMiddle AgedPredictive Value of TestsProof of Concept StudyProspective StudiesBioimpedanceECW/TBWhemodialysismortalityoverhydration

Identifiers

PMID33966595
PMCPMC8118427
OpenAlexW3161854123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.