Evidence map›Paper›PMID 33966537›Full record

ArticleJournal of child neurology2021

Susceptibility-Weighted Magnetic Resonance Imaging (MRI) of Microbleeds in Pediatric Concussion.

Shane Virani, Alexander Barton, Bradley G Goodyear, Keith Owen Yeates, Brian L Brooks

Open access · hybridAbstract read
In one paragraph

Article in Journal of child neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Emotional Regulation and Adolescent Concussion: Overview and Role of Neuroimaging.International journal of environmental research and public health · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shane ViraniDepartment of Pediatrics, 70402Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-3245-1581
Alexander BartonDepartment of Radiology, 2129University of Calgary, Calgary, Alberta, Canada.
Bradley G GoodyearDepartment of Radiology, 2129University of Calgary, Calgary, Alberta, Canada.
Keith Owen YeatesDepartment of Pediatrics, 2129University of Calgary, Calgary, Alberta, Canada.
Brian L BrooksDepartment of Pediatrics, Neurosciences Program, Alberta Children's Hospital, Calgary, Alberta, Canada.
University of Calgary · CA

Funding

CIHR
6 · The paper itself

Abstract

objectiveThe long-term consequences of pediatric concussion on brain structure are poorly understood. This study aimed to evaluate the presence and clinical significance of cerebral microbleeds several years after pediatric concussion.

methodsChildren and adolescents 8-19 years of age with either a history of concussion (n = 35), or orthopedic injury (n = 20) participated. Mean time since injury for the sample was 30.4 months (SD = 19.6). Participants underwent susceptibility-weighted imaging, rated their depression and postconcussion symptoms, and completed cognitive testing. Parents of participants also completed symptom ratings for their child. Hypointensities in susceptibility-weighted images indicative of cerebral microbleeds were calculated as a measure of hypointensity burden.

resultsHypointensity burden did not differ significantly between participants with a history of concussion and those with a history of orthopedic injury. Depression ratings (self and parent report), postconcussion symptom ratings (self and parent report), and cognitive performance did not significantly correlate with hypointensity burden in the concussion group.

conclusionsThese findings suggest that at approximately 2.5 years postinjury, children and adolescents with prior concussion do not have a greater amount of cerebral microbleeds compared to those with orthopedic injury. Future research should use longitudinal study designs and investigate children with persistent postconcussive symptoms to gain better insight into the long-term effects of concussion on cerebral microbleeds.

Indexed as

AdolescentAdultBrainBrain ConcussionCerebral HemorrhageChildFemaleHumansMagnetic Resonance ImagingMaleMicrovesselsYoung Adultadolescenceconcussionlong-termmicrobleedspediatricsusceptibility-weighted imaging

Identifiers

PMID33966537
PMCPMC8438780
OpenAlexW3162035294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.