Evidence map›Paper›PMID 33966361›Full record

Trial reportBiomolecular concepts2021

The Effects of Oral Liposomal Glutathione and In Vitro Everolimus in Altering the Immune Responses against

Kimberly To, Ruoqiong Cao, Aram Yegiazaryan, James Owens, Kayvan Sasaninia, Charles Vaughn, Mohkam Singh, Edward Truong, Airani Sathananthan, Vishwanath Venketaraman

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Biomolecular concepts, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Review
  3. Host-directed therapy for tuberculosis.European journal of medical research · 2025
    Review
  4. Review
  5. Immune Responses toBiomedicines · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Effects of Glutathione Diminishment on the Immune Responses againstApplied sciences (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kimberly ToGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Ruoqiong CaoCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, USA.
Aram YegiazaryanCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, USA.
James OwensCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, USA.
Kayvan SasaniniaGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Charles VaughnGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Mohkam SinghGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Edward TruongGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Airani SathananthanCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, USA.
Vishwanath VenketaramanGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA; College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, USA.
Western University of Health Sciences · US

Funding

Glutathione depletion in the CNS and its effects on Mtb infectionR15HL143545 · NHLBI · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI VENKETARAMAN, VISHWANATH · 2019 to 2024
$852k
NHLBI NIH HHS R15 HL143545
6 · The paper itself

Abstract

Tuberculosis (TB) caused by

Indexed as

Administration, OralAdolescentAdultAgedBCG VaccineCytokinesDiabetes Mellitus, Type 2Dietary SupplementsDouble-Blind MethodEverolimusFemaleGlutathioneGranulomaHumansImmunityImmunosuppressive AgentsBCG VaccineCytokinesEverolimusGlutathioneImmunosuppressive AgentscytokinesdiabeteseverolimusGlutathionehost-directed therapiesimmune responsesmycobacteria

Identifiers

PMID33966361
PMCPMC8975622
OpenAlexW3163764002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.