Effect of Blood Flow on Hemoglobin and Myoglobin Oxygenation in Contracting Muscle Using Near-Infrared Spectroscopy.

B Koirala, G M Saidel, A Hernández, L B Gladden, N Lai

Abstract read

In one paragraph

Article in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

Distinguishing Muscle Oxygen Saturation from Tissue Oxygen Saturation: Accuracy, Limitations, and Practical Utility in Muscle Oximetry.Sports medicine - open · 2026
Article
DCS blood flow index underestimates skeletal muscle perfusionJournal of biomedical optics · 2024
Article
Relationship between muscle venous blood oxygenation and near-infrared spectroscopy: quantitative analysis of the Hb and Mb contributions.Journal of applied physiology (Bethesda, Md. : 1985) · 2023
Article
Blood volume versus deoxygenated NIRS signal: computational analysis of the effects muscle OJournal of applied physiology (Bethesda, Md. : 1985) · 2021
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

B KoiralaDepartment of Electrical and Computer Engineering and Institute of Biomedical Engineering, Old Dominion University, Norfolk, VA, USA.

G M SaidelDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.

A HernándezOffice of Research and Economic Development, University of California, Merced, Merced, CA, USA.

L B GladdenDepartment of Kinesiology, Auburn University, Auburn, AL, USA.

N LaiDepartment of Electrical and Computer Engineering and Institute of Biomedical Engineering, Old Dominion University, Norfolk, VA, USA. nlai@odu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insufficient O

Indexed as

MyoglobinSpectroscopy, Near-InfraredExerciseHemodynamicsHemoglobinsHumansMuscle, SkeletalOxygenOxygen ConsumptionHemoglobinsMyoglobinOxygenComputational modelingExerciseMetabolic fluxNIRSOxygen delivery

Identifiers

PMID33966244

DOI10.1007/978-1-4419-7756-4_47

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.