ArticleEnvironmental science and pollution research international2021
Association between prenatal phthalate exposure and anthropometric measures of newborns in a sample of Iranian population.
Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Article
- Association of prenatal exposure to phthalates with risks of asthma, wheeze, and allergic diseases during childhood: a systematic review and meta-analysis.Journal of environmental health science & engineering · 2025Article
- Characteristics and pollution indices of leachates from municipal solid waste landfills in Iranian metropolises and their implications for MSW management.Scientific reports · 2024Article
- Association between type of drinking water and upper gastrointestinal cancer incidence in the Linxian General Population.BMC cancer · 2023Article
- Exposure of preterm neonates receiving total parenteral nutrition to phthalates and its impact on neurodevelopment at the age of 2 months.Scientific reports · 2023Article
- Article
- Modulation of fetoplacental growth, development and reproductive function by endocrine disrupters.Frontiers in endocrinology · 2023Review
- Association between urinary phthalate levels and chronic pain in US adults, 1999-2004: A nationally representative survey.Frontiers in neurology · 2023Article
- The association between blood heavy metals level and sex hormones among postmenopausal women in the US.Frontiers in endocrinology · 2023Article
- Concentrations of urinary parabens and reproductive hormones in Iranian women: Exposure and risk assessment.Toxicology reports · 2022Article
- Monitoring of urinary arsenic (As) and lead (Pb) among a sample of pregnant Iranian women.Journal of environmental health science & engineering · 2021Article
- Prenatal exposure to chromium (Cr) and nickel (Ni) in a sample of Iranian pregnant women: urinary levels and associated socio-demographic and lifestyle factors.Environmental science and pollution research international · 2021Article
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Authors and funding
9 authors.
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Abstract
Phthalates or phthalic acid esters (PAEs) are a group of compounds which they can be entered into the human body through the various pathways. The aim of this study was to examine associations between prenatal phthalates exposure with anthropometric measures of neonates. Urine samples were obtained from 121 Iranian pregnant women at their first trimester of pregnancy, and the levels of monobutyl phthalate (MBP), mono-benzyl phthalate (MBzP), mono-2-ethylhexyl phthalate (MEHP), and mono (2-ethyl-5hydroxyhexyl) phthalate (MEHHP) metabolites were determined by gas chromatography mass spectrometry (GC/MS). The correlations between the maternal urinary concentrations of phthalate metabolites with anthropometric measures of neonates as well as with the socio-demographic factors of participants (maternal education, age, family income, pre-pregnancy body mass index), their lifestyle variables (smoking habit, food pattern, and physical activity), and use of cleaning products (cosmetic and household cleaning products) were investigated. MBzP, MBP, MEHP, and MEHHP were detected in 100% of the participants with the concentration ranged 120 to 860 μg/g creatinine. Significant correlations were observed between the urinary levels of maternal MBzP (adjusted β = 0.3 (0.001), p = 0.03) and MEHHP (adjusted β = 0.3 (0.001), p = 0.04) with the birth weight of female neonates. MBP (adjusted β = -0.3 (0.02), p = 0.04) and MBzP (adjusted β = -0.3 (0.001), p = 0.02) had negative associations with the head circumference in male and female newborns, respectively. Furthermore, plastic packaging for pickle and passive smoking during pregnancy were identified to be significantly associated with low birth weight (p value < 0.05). Iranian pregnant women had higher concentrations of urinary phthalates compared to the other countries. Based on the findings, the higher prenatal exposure to phthalates could adversely impact the health status of newborns.
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