ArticleDiabetologia2021
A UK nationwide study of people with type 1 diabetes admitted to hospital with COVID-19 infection.
Article in Diabetologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Risk phenotypes of diabetes and association with COVID-19 severity and death: an update of a living systematic review and meta-analysis.Diabetologia · 2023Pooled it
- Pre-existing diabetic retinopathy as a prognostic factor for COVID-19 outcomes amongst people with diabetes: A systematic review.Diabetes research and clinical practice · 2022Pooled it
- Microvascular disease and severe COVID-19 outcomes in UKBiobank participants with diabetes.Acta diabetologica · 2025Review
- Japanese medical researchers' perceptions of quantitative research evaluation metrics and their psychological well-being: a cross-sectional study.Environmental health and preventive medicine · 2025Article
- Relationships between Lip Seal Strength, Tongue Pressure, and Daytime Sleepiness in Japanese Workers: A Cross-Sectional Study.Clinics and practice · 2023Article
- Lip Seal Strength and Tongue Pressure among Japanese Male Workers: Comparison of Different Age Groups.International journal of environmental research and public health · 2023Article
- Impact of Japan's State of Emergency Due to the COVID-19 Pandemic on Trends in Diabetes Care: A Descriptive and Retrospective Study.Clinics and practice · 2023Article
- Type 1 diabetes mellitus and SARS-CoV-2 in pediatric and adult patients - Data from the DPV network.Journal of diabetes · 2022Article
- COVID-19 Vaccination-Induced Cholangiopathy and Autoimmune Hepatitis: A Series of Two Cases.Cureus · 2022Article
- Improved glucometrics in people with type 1 diabetes 1 year into the COVID-19 pandemic.BMJ open diabetes research & care · 2022Observational
- COVID-19 and Diabetes Outcomes: Rationale for and Updates from the CORONADO Study.Current diabetes reports · 2022Review
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Authors and funding
24 authors at 15 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
aims/hypothesisThe aim of this work was to describe the clinical characteristics of adults with type 1 diabetes admitted to hospital and the risk factors associated with severe coronavirus disease-2019 (COVID-19) in the UK.
methodsA retrospective cohort study was performed using data collected through a nationwide audit of people admitted to hospital with diabetes and COVID-19, conducted by the Association of British Clinical Diabetologists from March to October 2020. Prespecified demographic, clinical, medication and laboratory data were collected from the electronic and paper medical record systems of the participating hospitals by local clinicians. The primary outcome of the study, severe COVID-19, was defined as death in hospital and/or admission to the adult intensive care unit (AICU). Logistic regression models were used to generate age-adjusted ORs.
resultsForty UK centres submitted data. The final dataset included 196 adults who were admitted to hospital and had both type 1 diabetes and COVID-19 on admission (male sex 55%, white 70%, with mean [SD] age 62 [19] years, BMI 28.3 [7.3] kg/m CONCLUSIONS/
interpretationIn people with type 1 diabetes and COVID-19 who were admitted to hospital in the UK, higher BMI, poorer renal function and presence of microvascular complications were associated with greater risk of death and/or admission to AICU. Risk of severe COVID-19 is reassuringly very low in people with type 1 diabetes who are under 55 years of age without microvascular or macrovascular disease. IN PEOPLE WITH TYPE 1 DIABETES AND COVID-19 ADMITTED TO HOSPITAL IN THE UK, BMI AND ONE OR MORE MICROVASCULAR COMPLICATIONS HAD A POSITIVE ASSOCIATION AND LOW SERUM CREATINE LEVELS HAD A NEGATIVE ASSOCIATION WITH DEATH/ADMISSION TO INTENSIVE CARE UNIT AFTER ADJUSTING FOR AGE.
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