Evidence map›Paper›PMID 33964949›Full record

ArticleEnvironmental health : a global access science source2021

Joint effects of ethnic enclave residence and ambient volatile organic compounds exposure on risk of gestational diabetes mellitus among Asian/Pacific Islander women in the United States.

Andrew D Williams, Sandie Ha, Edmond Shenassa, Lynne C Messer, Jenna Kanner, Pauline Mendola

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Andrew D WilliamsPublic Health program, Department of Population Health, School of Medicine & Health Sciences, University of North Dakota, Room E162, 1301 North Columbia Road Stop 9037, Grand Forks, ND, 58202-9037, USA. andrew.d.williams@und.edu.ORCID 0000-0002-0411-3171
Sandie HaSchool of Social Sciences, Humanities and Arts, Health Science Research Institute, University of California, 5200 N. Lake Road, Merced, CA, USA.
Edmond ShenassaMaternal and Child Health Program, Department of Family Science, University of Maryland College Park, 4200 Valley Drive, College Park, MD, USA.
Lynne C MesserOHSU-PSU School of Public Health, Portland State University, 506 SW Mill Street 470H, Portland, OR, USA.
Jenna KannerEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6710B Rockledge Drive, MSC, Bethesda, MD, 7004, USA.
Pauline MendolaEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6710B Rockledge Drive, MSC, Bethesda, MD, 7004, USA.
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USPortland State University · USUniversity of California, Merced · USUniversity of Maryland, College Park · USUniversity of North Dakota · US

Funding

SYNERGY: The Dartmouth Center for clinical and Translational ScienceUL1TR001086 · NCATS · DARTMOUTH COLLEGE · PI GREEN, ALAN I · 2013 to 2017
$18.3M
Sci-Tech Core-Maryland Population Research CenterP2CHD041041 · NICHD · UNIV OF MARYLAND, COLLEGE PARK · PI Susan W Parker · 2018 to 2026
$3.9M
NCATS NIH HHS UL1 TR001086NICHD NIH HHS HHSN267200603425CNICHD NIH HHS HHSN27500008NICHD NIH HHS HHSN275200800002CNICHD NIH HHS HHSN275200800002INICHD NIH HHS P2C HD041041
6 · The paper itself

Abstract

backgroundAsian/Pacific Islander (API) communities in the United States often reside in metropolitan areas with distinct social and environmental attributes. Residence in an ethnic enclave, a socially distinct area, is associated with lower gestational diabetes mellitus (GDM) risk, yet exposure to high levels of air pollution, including volatile organic compounds (VOCS), is associated with increased GDM risk. We examined the joint effects of ethnic enclaves and VOCs to better understand GDM risk among API women, the group with the highest prevalence of GDM.

methodsWe examined 9069 API births in the Consortium on Safe Labor (19 hospitals, 2002-2008). API ethnic enclaves were defined as areas ≥66th percentile for percent API residents, dissimilarity (geographic dispersal of API and White residents), and isolation (degree that API individuals interact with another API individual). High levels of 14 volatile organic compounds (VOC) were defined as ≥75th percentile. Four joint categories were created for each VOC: Low VOC/Enclave (reference group), Low VOC/No Enclave, High VOC/Enclave, High VOC/No Enclave. GDM was reported in medical records. Hierarchical logistic regression estimated odds ratios (OR) and 95% confidence intervals (95%CI) between joint exposures and GDM, adjusted for maternal factors and area-level poverty. Risk was estimated for 3-months preconception and first trimester exposures.

resultsEnclave residence was associated with lower GDM risk regardless of VOC exposure. Preconception benzene exposure was associated with increased risk when women resided outside enclaves [High VOC/No Enclave (OR:3.45, 95%CI:1.77,6.72)], and the effect was somewhat mitigated within enclaves, [High VOC/Enclave (OR:2.07, 95%:1.09,3.94)]. Risks were similar for 12 of 14 VOCs during preconception and 10 of 14 during the first trimester.

conclusionsAPI residence in non-enclave areas is associated with higher GDM risk, regardless of VOC level. Ethnic enclave residence may mitigate effects of VOC exposure, perhaps due to lower stress levels. The potential benefit of ethnic enclaves warrants further study.

Indexed as

Asian PeopleNative Hawaiian or Pacific IslanderAdultAir PollutantsDiabetes, GestationalEnvironmental ExposureFemaleHumansPregnancyResidence CharacteristicsRiskUnited StatesVolatile Organic CompoundsYoung AdultAir PollutantsVolatile Organic CompoundsAir pollutionAsian/Pacific IslandersEthnic enclaveGestational Diabetes MellitusJoint exposurePregnancyStressVolatile Organic Compounds

Identifiers

PMID33964949
PMCPMC8106843
OpenAlexW3130582948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.