ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2021
Amygdalar Activation as a Neurobiological Marker of Differential Sensitivity in the Effects of Family Rearing Experiences on Socioemotional Adjustment in Youths.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 22 citations in OpenAlex.
- Neural and psychological predictors of digital status-seeking in adolescence.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026Article
- Neural Predictors of Vaping: Covert Emotional Engagement Versus Reactance to Overt Emotional Appeals in Vaping Prevention Message Processing.American journal of preventive medicine · 2026Article
- Perceived Maternal Overprotection and Amygdala Functional Connectivity in Children: Implications for Childhood Depressive Symptoms.Depression and anxiety · 2026Article
- Parental warmth buffers the negative impact of weaker fronto-striatal connectivity on early adolescents' academic achievement.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025Article
- Strengthening through adversity: The hormesis model in developmental psychopathology.Development and psychopathology · 2024Article
- Environmental and neurodevelopmental contributors to youth mental illness.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Racial Discrimination and Risk for Internalizing and Externalizing Symptoms Among Black Youths.JAMA network open · 2024Article
- In or out of sync? Concordance between parent and adolescent sleep varies by family context.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2023Article
- The longitudinal role of family conflict and neural reward sensitivity in youth's internalizing symptoms.Social cognitive and affective neuroscience · 2023Article
- Network analysis of emotion regulation and reactivity in adolescents: identifying central components and implications for anxiety and depression interventions.Frontiers in psychiatry · 2023Article
- Continuity versus change in latent profiles of emotion regulation and working memory during adolescence.Developmental cognitive neuroscience · 2022Article
- Early experience unpredictability in child development as a model for understanding the impact of the COVID-19 pandemic: A translational neuroscience perspective.Developmental cognitive neuroscience · 2022Article
- The reciprocal relationships between Chinese children's perception of interparental conflict, negative thinking, and depression symptoms: A cross-lagged study.Frontiers in psychology · 2022Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
backgroundSubstantial heterogeneity exists in how rearing environments influence youths' socioemotional outcomes. This heterogeneity, as suggested by the biological sensitivity to context theory and the differential susceptibility theory, is associated with emotional reactivity patterns and underlying neural functions. The present study investigated amygdalar reactivity to emotional stimuli as a neural signature that amplified the influence of rearing environments on youths' socioemotional outcomes.
methodsTo increase replicability and generalizability, this investigation included two independent studies that methodologically complemented each other. Study 1 employed a large, national, longitudinal dataset (the Adolescent Brain Cognitive Development study; N = 11,875). Study 2 used a community sample of youths (N = 123) with multimethod and multireporter assessments.
resultsIn study 1, high left amygdalar reactivity to positive stimuli significantly amplified the impact of parental warmth on youths' prosocial behaviors. In study 2, left and right amygdalar reactivity to positive stimuli significantly intensified the associations between family functioning and youths' internalizing problems. These findings were consistent with the biological sensitivity to context theory/differential susceptibility theory hypothesis because significant socioemotional differences were observed at both negative and positive extremes of rearing environments. Additionally, study 2 partially supported the diathesis-stress hypothesis by showing significant differences in youths' vulnerability to negative family environments. Specifically, left amygdalar response to negative stimuli exacerbated the associations between unbalanced family functioning and heightened internalizing/externalizing symptoms. Left amygdalar reactivity to positive stimuli intensified the link between unbalanced family functioning and elevated externalizing problems.
conclusionsAmong youths and adolescents, amygdalar emotional reactivity may serve as a biomarker of differential sensitivity to rearing environments.
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