Evidence map›Paper›PMID 33964415›Full record

Trial reportContemporary clinical trials2021

Predictors of attrition in a smoking cessation trial conducted in the lung cancer screening setting.

Emily Kim, Randi M Williams, Ellie Eyestone, Marisa Cordon, Laney Smith, Kimberly Davis, George Luta, Eric D Anderson, Brady McKee, Juan Batlle and 9 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03200236 (Integrating Evidence-Based Smoking Cessation Interventions Into Lung Cancer Screening Programs), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03200236 phase3completednot on this map

Integrating Evidence-Based Smoking Cessation Interventions Into Lung Cancer Screening Programs: A Randomized Trial

TypeinterventionalSponsorGeorgetown UniversityRan2017 to 2022Enrolled1,114ConditionsSmoking, Tobacco, Tobacco-Related Carcinoma, Tobacco Use, Lung Cancer ScreeningArmsIntensive Telephone Counseling (8 sessions) with nicotine replacement, Usual Care: Telephone counseling (3 sessions) with nicotine replacement
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Attitudes towards the integration of smoking cessation into lung cancer screening in the United Kingdom: A qualitative study of individuals eligible to attend.Health expectations : an international journal of public participation in health care and health policy · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 1 country.

Emily KimGeorgetown University Medical Center, D.C., USA.
Randi M WilliamsGeorgetown University Medical Center, D.C., USA.
Ellie EyestoneGeorgetown University Medical Center, D.C., USA.
Marisa CordonGeorgetown University Medical Center, D.C., USA.
Laney SmithGeorgetown University Medical Center, D.C., USA.
Kimberly DavisGeorgetown University Medical Center, D.C., USA.
George LutaGeorgetown University Medical Center, D.C., USA.
Eric D AndersonGeorgetown University Medical Center, D.C., USA.
Brady McKeeLahey Hospital and Medical Center, Burlington, MA, USA.
Juan BatlleBaptist Health South Florida, Miami, FL, USA.
Michael RamsaierHackensack University Medical Center, Hackensack, NJ, USA.
Judith HowellUnityPoint Health, Quad Cities, USA.
Vicky ParikhMedStar Shah Medical Group, Hollywood, MD, USA.
Maria GeronimoAnne Arundel Medical Center, Annapolis, MD, USA.
Cassandra StantonWestat, Rockville, MD, USA.
Raymond NiauraNew York University, New York City, NY, USA.
David AbramsNew York University, New York City, NY, USA.
Kathryn L TaylorGeorgetown University Medical Center, D.C., USA. Electronic address: taylorkl@georgetown.edu.
Lung Screening, Tobacco and Health Trial
Georgetown University · USGeorgetown University Medical Center · USNew York University · USAnne Arundel Medical Center · USBaptist Health South Florida · USHackensack University Medical Center · USHematology Oncology Associates · USLahey Medical Center · USWestat (United States) · US

Funding

Integrating Evidence-Based Smoking Cessation Interventions into Lung Cancer Screening Programs: A Randomized TrialR01CA207228 · NCI · GEORGETOWN UNIVERSITY · PI TAYLOR, KATHRYN L · 2016 to 2020
$3.5M
NCI NIH HHS R01 CA207228
6 · The paper itself

Abstract

significanceAlthough it is a requirement that tobacco treatment is offered to cigarette smokers undergoing low-dose computed tomographic lung cancer screening (LCS), not all smokers engage in treatment. To understand the barriers to tobacco treatment in this setting, we evaluated predictors of attrition in a smoking cessation trial among individuals undergoing LCS.

methodsPrior to LCS, 926 participants, 50-80 years old, completed the baseline (T0) phone assessment, including demographic, clinical, tobacco, and psychological characteristics. Following LCS and receipt of the results, participants completed the pre-randomization (T1) assessment.

resultsAt the T1 assessment, 735 (79%) participants were retained and 191 (21%) dropped out. In multivariable analyses, attrition was higher among those who: smoked >1 pack per day (OR = 1.44, CI 1.01, 2.06) or had undergone their first (vs. annual) LCS scan (OR = 1.70, CI 1.20, 2.42). Attrition was lower among those with: more education (associates (OR = 0.67, CI = 0.46, 0.98) or bachelor's degree (OR = 0.56, CI 0.35, 0.91) vs. high school/GED), some (vs. none/a little) worry about lung cancer (OR = 0.60, CI 0.39, 0.92), or a screening result that was benign (OR = 0.57, CI 0.39, 0.82) or probably benign (OR = 0.38, CI 0.16, 0.90) vs. negative.

conclusionsThis study illuminated several LCS-related factors that contributed to trial attrition. Increasing tobacco treatment in this setting will require targeted strategies for those who report little lung cancer worry, are undergoing their first LCS exam, and/or who have a negative LCS result. Addressing attrition and reducing barriers to tobacco treatment will increase the likelihood of cessation, thereby reducing the risk of developing lung cancer.

Indexed as

Lung NeoplasmsSmoking CessationAgedAged, 80 and overEarly Detection of CancerHumansMass ScreeningMiddle AgedSmokersClinical trialLow-dose computed tomographic lung cancer screeningSmoking cessationTrial attrition

Identifiers

PMID33964415
PMCPMC8686204
OpenAlexW3159262062

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.