Evidence map›Paper›PMID 33964244›Full record

Observational studyThe Lancet. Respiratory medicine2021

Early humoral response among lung transplant recipients vaccinated with BNT162b2 vaccine.

Yael Shostak, Noa Shafran, Moshe Heching, Dror Rosengarten, Osnat Shtraichman, Dorit Shitenberg, Shai M Amor, Dafna Yahav, Haim Ben Zvi, Barak Pertzov and 1 more

Registry-linked trialOpen access · bronzeAbstract readLetterObservational Study
In one paragraph

Observational study in The Lancet. Respiratory medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05280158 (Phase I/II, Open-Label Dose-Finding Trial of High-Dose mRNA-1273 Booster for Lung Transplant Recipients), which is not on this map. Cited by 48 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 5 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05280158 phase1 / phase2terminatednot on this mapstarted 2022, after this paper: background citation

Phase I/II, Open-Label Dose-Finding Trial of High-Dose mRNA-1273 Booster for Lung Transplant Recipients

TypeinterventionalSponsorUniversity of California, Los AngelesRan2022 to 2023Enrolled19ConditionsLung Transplant Recipient, SARS-CoV-2, ImmunosuppressionArmsmRNA-1273 (Moderna COVID-19 vaccine)
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Immunogenicity of COVID-19 vaccines in solid organ transplant recipients: a systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2023
    Pooled it
  2. Humoral and cellular response of COVID-19 vaccine among solid organ transplant recipients: A systematic review and meta-analysis.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Pooled it
  3. Pooled it
  4. Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Pooled it
  5. Pooled it
  6. Review
  7. Article
  8. Article
  9. Risk of severe COVID in solid organ transplant recipient.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Predominantly defective CD8Journal of translational medicine · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Clinical course of SARS-CoV-2 infection and recovery in lung transplant recipients.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yael ShostakDepartment of Medicine D, Rabin Medical Center, Petach Tikva, Israel; Pulmonary Division, Rabin Medical Center, Petach Tikva 49100, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: yaelsho2@clalit.org.il.
Noa ShafranDepartment of Medicine D, Rabin Medical Center, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Moshe HechingPulmonary Division, Rabin Medical Center, Petach Tikva 49100, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Dror RosengartenPulmonary Division, Rabin Medical Center, Petach Tikva 49100, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Osnat ShtraichmanPulmonary Division, Rabin Medical Center, Petach Tikva 49100, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Dorit ShitenbergPulmonary Division, Rabin Medical Center, Petach Tikva 49100, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Shai M AmorPulmonary Division, Rabin Medical Center, Petach Tikva 49100, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Dafna YahavSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Infectious Disease Unit, Rabin Medical Center, Petach Tikva, Israel.
Haim Ben ZviSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Microbiology Laboratory, Rabin Medical Center, Petach Tikva, Israel.
Barak PertzovPulmonary Division, Rabin Medical Center, Petach Tikva 49100, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Mordechai R KramerPulmonary Division, Rabin Medical Center, Petach Tikva 49100, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tel Aviv University · ILRabin Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lung TransplantationAdultAgedBNT162 VaccineCohort StudiesCOVID-19 VaccinesFemaleHumansIsraelMaleMiddle AgedProspective StudiesTransplant RecipientsBNT162 VaccineCOVID-19 Vaccines

Identifiers

PMID33964244
PMCPMC8099313
OpenAlexW3159720309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.