ArticleBioinformatics (Oxford, England)2021
Reactome and the Gene Ontology: digital convergence of data resources.
Article in Bioinformatics (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- The Gene Ontology knowledgebase in 2026.Nucleic acids research · 2026Article
- Small Non-Coding RNAs and Their Role in Locoregional Metastasis and Outcomes in Early-Stage Breast Cancer Patients.International journal of molecular sciences · 2024Article
- Enrichment on steps, not genes, improves inference of differentially expressed pathways.PLoS computational biology · 2024Article
- The Reactome Pathway Knowledgebase 2024.Nucleic acids research · 2024Article
- Decoding semiotic minimal genome: a non-genocentric approach.Frontiers in microbiology · 2024Article
- Semantic representation of neural circuit knowledge in Caenorhabditis elegans.Brain informatics · 2023Article
- Article
- Semantic Representation of Neural Circuit Knowledge inbioRxiv : the preprint server for biology · 2023Article
- Biochemical Pathways Represented by Gene Ontology Causal Activity Models Identify Distinct Phenotypes Resulting from Mutations in Pathways.bioRxiv : the preprint server for biology · 2023Article
- The Gene Ontology knowledgebase in 2023.Genetics · 2023Review
- Article
- Immunogenic cell death-led discovery of COVID-19 biomarkers and inflammatory infiltrates.Frontiers in microbiology · 2023Article
- Differential microRNA profiles in elderly males with seborrheic dermatitis.Scientific reports · 2022Article
- On the influence of several factors on pathway enrichment analysis.Briefings in bioinformatics · 2022Review
- Article
- Rhea, the reaction knowledgebase in 2022.Nucleic acids research · 2022Article
- Article
- Mass spectrometry methods for analysis of extracellular matrix components in neurological diseases.Mass spectrometry reviewsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 1 country.
Funding
Abstract
motivationGene Ontology Causal Activity Models (GO-CAMs) assemble individual associations of gene products with cellular components, molecular functions and biological processes into causally linked activity flow models. Pathway databases such as the Reactome Knowledgebase create detailed molecular process descriptions of reactions and assemble them, based on sharing of entities between individual reactions into pathway descriptions.
resultsTo convert the rich content of Reactome into GO-CAMs, we have developed a software tool, Pathways2GO, to convert the entire set of normal human Reactome pathways into GO-CAMs. This conversion yields standard GO annotations from Reactome content and supports enhanced quality control for both Reactome and GO, yielding a nearly seamless conversion between these two resources for the bioinformatics community. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.