Evidence map›Paper›PMID 33964115›Full record

ReviewAndrology2021

When to ask for an MRI of the scrotum.

Athina C Tsili, Maria I Argyropoulou, Miriam Dolciami, Giada Ercolani, Carlo Catalano, Lucia Manganaro

Open access · hybridAbstract readReview
In one paragraph

Review in Andrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Athina C TsiliDepartment of Clinical Radiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Maria I ArgyropoulouDepartment of Clinical Radiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Miriam DolciamiDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Roma, Italy.
Giada ErcolaniDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Roma, Italy.
Carlo CatalanoDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Roma, Italy.
Lucia ManganaroDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Roma, Italy.ORCID 0000-0001-9037-9904
Sapienza University of Rome · ITUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiparametric MRI (mpMRI) of the scrotum has been established as a useful second-line diagnostic tool for the investigation of scrotal diseases. Recently, recommendations on clinical indications for scrotal MRI were issued by the Scrotal and Penile Imaging Working Group of the European Society of Urogenital Radiology.

objectiveTo update current research on when to ask for an MRI of the scrotum.

methodsPubMed database was searched for original articles and reviews published during 2010-2021.

resultsEighty-three articles fulfilled the search criteria. Scrotal MRI is mainly recommended after inconclusive US findings or inconsistent with the clinical examination and should be asked in the following cases: differentiation between intratesticular and paratesticular lesions (in rare cases of uncertain US findings), characterization of paratesticular and intratesticular lesions (when US findings are indeterminate), discrimination between germ cell and sex cord-stromal testicular tumors, local staging of testicular malignancies (in patients planned for testis-sparing surgery), differentiation between seminomas and non-seminomatous tumors (when immediate chemotherapy is planned and orchiectomy is delayed), assessment of acute scrotum and scrotal trauma (rarely needed, in cases of non-diagnostic US findings) and detection and localization of undescended testes (in cases of inconlusive US findings). Although preliminary data show promising results in the evaluation of male infertility, no established role for mpMRI still exists.

conclusionMultiparametric MRI of the scrotum, by assessing morphologic and functional data represents a valuable problem-solving tool, helping to improve our understanding on the nature of scrotal pathology and the process of spermatogenesis. The technique may improve patient care and reduce the number of unnecessary surgical procedures.

Indexed as

Diagnosis, DifferentialHumansMagnetic Resonance ImagingMalePractice Guidelines as TopicScrotumSocieties, MedicalTesticular Diseasesmagnetic resonance imagingmultiparametric magnetic resonance imagingscrotumtesticular neoplasmstestis

Identifiers

PMID33964115
PMCPMC8596813
OpenAlexW3159138807

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.