ArticleInternational journal of health economics and management2022
Opioid and non-opioid analgesic prescribing before and after the CDC's 2016 opioid guideline.
Article in International journal of health economics and management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Patient- and Clinician-Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non-Cancer Pain: A Systematic Review.Clinical pharmacology and therapeutics · 2026Pooled it
- Acupuncture Therapy as an Evidence-Based Nonpharmacologic Strategy for Comprehensive Acute Pain Care: The Academic Consortium Pain Task Force White Paper Update.Pain medicine (Malden, Mass.) · 2022Pooled it
- Temporal trends in gabapentinoid use for the acute management of spinal cord injury: a retrospective cohort study.Spinal cord · 2026Article
- Factors associated with nonpharmacological treatment use among older adults with chronic low back pain tapering opioids.Pain management · 2025Article
- Prescription Opioid Use in Older Adults: Trends and Changes in New and Long-Term Use in the United States, 2013-2020.Drugs & aging · 2025Article
- Trends in Drug Claims for Non-Specific Low Back Pain in Québec, 1997 to 2018.Musculoskeletal care · 2025Article
- Trends in Celecoxib Prescribing: A Single Institution 16-Month Review.Journal of clinical medicine · 2025Article
- Incidence of Opioid Dose Tapering Among Older Adults Enrolled in Medicare.Innovation in aging · 2025Article
- High-risk use of prescription opioids among patients treated for alcohol problems in New York State. A repeated cross-sectional study, 2005-2018.Drug and alcohol dependence reports · 2024Article
- Opioid and non-opioid analgesic regimens after fracture and risk of serious opioid-related events.Trauma surgery & acute care open · 2024Article
- Changes in Prescribed Opioid Dosages Among Patients Receiving Medical Cannabis for Chronic Pain, New York State, 2017-2019.JAMA network open · 2023Article
- Self-Reported Pain Treatment Practices Among U.S. and Canadian Adults: Findings From a Population Survey.Innovation in aging · 2023Article
- Trends in the Use of Opioids vs Nonpharmacologic Treatments in Adults With Pain, 2011-2019.JAMA network open · 2022Article
- Trends in Prescriptions for Non-opioid Pain Medications Among U.S. Adults With Moderate or Severe Pain, 2014-2018.The journal of pain · 2022Article
- Comment from the Academic Consortium for Integrative Medicine & Health on the CDC Clinical Practice Guideline for Prescribing Opioids-United States, 2022.Global advances in health and medicine · 2022Article
- Opioid Dosage Levels, Concurrent Risk Factors and Self-Perceptions among Chronic Pain, Opioid-Managed Individuals at Elevated Risk for Opioid Overdose.Pharmaceuticals (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The U.S. has addressed the opioid crisis using a two-front approach: state regulations limiting opioid prescriptions for acute pain patients, and voluntary federal CDC guidelines on shifting chronic pain patients to lower opioid doses and non-opioids. No opioid policy research to date has accounted for this two-pronged approach in their research design. We develop a theory of physician prescribing behavior under this two-pronged incentive structure. Using the Medical Expenditure Panel Survey, we empirically corroborate the theory: regulations and guidelines have the intended effects of reducing opioid prescriptions for acute and chronic pain, respectively, as well as the predicted unintended effects-income effects cause regulations on acute pain treatment to increase chronic pain opioid prescriptions and the chronic pain treatment guidelines spillover to reduce opioids for acute pain. Moreover, we find that the guidelines worked as intended in terms of the reduced usage, with chronic pain patients shifting to non-opioids and also tapering opioid doses. For those who discontinued opioids under regulations and guidelines, we find no harm in terms of increased work limitations due to pain a year after discontinuing opioids. Finally, we observe an unexplained dichotomy-regulations reduce opioid use by causing fewer new starts, whereas guidelines reduce opioid use by discontinuing current users, with no impact on new starts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.