Evidence map›Paper›PMID 33963967›Full record

ArticleForensic science, medicine, and pathology2021

Post-mortem persistence of SARS-CoV-2: a preliminary study.

Sara Sablone, Biagio Solarino, Davide Ferorelli, Marcello Benevento, Maria Chironna, Daniela Loconsole, Anna Sallustio, Alessandro Dell'Erba, Francesco Introna

Open access · hybridAbstract read
In one paragraph

Article in Forensic science, medicine, and pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Safe autopsy procedures for COVID-19: Experience of one research center.Journal of neuropathology and experimental neurology · 2025
    Article
  5. Review
  6. RT-PCR Result of SARS-CoV-2 Viral RNA in Cadavers and Viral Transmission Risk to Handlers.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Rate of shed of SARS COV-2 viral RNA from COVID-19 cadavers.Journal of infection and public health · 2022
    Article
  11. Article
  12. Article
  13. SARS-CoV-2 viral load and replication in postmortem examinations.International journal of legal medicine · 2022
    Article
  14. Article
  15. Article
  16. Olfactory Bulb and Amygdala Gene Expression Changes in Subjects Dying with COVID-19.medRxiv : the preprint server for health sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sara SabloneSection of Legal Medicine, Department of Interdisciplinary Medicine, Bari Policlinico Hospital, University of Bari, 70124, Bari, Italy.
Biagio SolarinoSection of Legal Medicine, Department of Interdisciplinary Medicine, Bari Policlinico Hospital, University of Bari, 70124, Bari, Italy. biagio.solarino@uniba.it.
Davide FerorelliSection of Legal Medicine, Department of Interdisciplinary Medicine, Bari Policlinico Hospital, University of Bari, 70124, Bari, Italy.
Marcello BeneventoSection of Legal Medicine, Department of Interdisciplinary Medicine, Bari Policlinico Hospital, University of Bari, 70124, Bari, Italy.
Maria ChironnaSection of Hygiene, Department of Biomedical Sciences and Human Oncology, Bari Policlinico Hospital, University of Bari, 70124, Bari, Italy.
Daniela LoconsoleSection of Hygiene, Department of Biomedical Sciences and Human Oncology, Bari Policlinico Hospital, University of Bari, 70124, Bari, Italy.
Anna SallustioSection of Hygiene, Department of Biomedical Sciences and Human Oncology, Bari Policlinico Hospital, University of Bari, 70124, Bari, Italy.
Alessandro Dell'ErbaSection of Legal Medicine, Department of Interdisciplinary Medicine, Bari Policlinico Hospital, University of Bari, 70124, Bari, Italy.
Francesco IntronaSection of Legal Medicine, Department of Interdisciplinary Medicine, Bari Policlinico Hospital, University of Bari, 70124, Bari, Italy.
University of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the beginning of March 2020, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been the cause of millions of deaths worldwide. The need to better define the pathogenesis of coronavirus disease 19 (Covid-19) as well as to provide the correct statistical records concerning deaths related to this virus, inevitably involves the role of forensic pathology and routine autopsy practice. Currently, some data on macroscopic and microscopic features in autopsies performed in suspected Covid-19 cases are reported in the literature. The persistence of SARS-CoV-2 in cadavers has not yet been elucidated and only a few reports have emphasized the importance of evaluating the Virus RNA in post-mortem tissues. In this preliminary study, we observed that SARS-CoV-2 survives in multiple cadaver tissues many days after death despite some extreme conditions of post-mortem body preservation. The results of this on-going analysis could help improve the safety of working practices for pathologists as well as understanding the possible interaction between microbiological agents and the cadaver tissue's supravital reactions.

Indexed as

COVID-19SARS-CoV-2AutopsyCadaverHumansPandemicsCadaver tissue samplesCOVID-19 autopsyPost-mortem intervalSARS-CoV-2Viral RNA

Identifiers

PMID33963967
PMCPMC8105695
OpenAlexW3158680326

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.