Evidence map›Paper›PMID 33963934›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2021

Low-molecular-mass labile metal pools in Escherichia coli: advances using chromatography and mass spectrometry.

Hayley N Brawley, Paul A Lindahl

Open access · hybridAbstract read
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. The E. coli escape wave in response to external ZnBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
  2. Review
  3. Article
  4. The Labile Side of Iron in Health and Disease: A Narrative Review.Advances in experimental medicine and biology · 2025
    Review
  5. Direct relationship between dimeric form and activity in the acidic copper-zinc superoxide dismutase from lemon.Acta crystallographica. Section F, Structural biology communications · 2023
    Article
  6. Article
  7. Article
  8. Yeast Mitochondria Import Aqueous FeJournal of the American Chemical Society · 2023
    Article
  9. Labile Iron Pool of IsolatedJournal of the American Chemical Society · 2023
    Article
  10. Article
  11. Mitochondrial copper in human genetic disorders.Trends in endocrinology and metabolism: TEM · 2023
    Review
  12. Review
  13. Protein metalation in biology.Current opinion in chemical biology · 2022
    Review
  14. Direct Detection of the Labile Nickel Pool inJournal of the American Chemical Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hayley N BrawleyDepartment of Chemistry, Texas A&M University, College Station, TX, 77843-3255, USA.
Paul A LindahlDepartment of Chemistry, Texas A&M University, College Station, TX, 77843-3255, USA. Lindahl@chem.tamu.edu.ORCID 0000-0001-8307-9647
Texas A&M University · US

Funding

Iron Trafficking and Regulation in Biological SystemsR35GM127021 · NIGMS · TEXAS A&M UNIVERSITY · PI PAUL A. LINDAHL · 2018 to 2026
$3.4M
NIGMS NIH HHS GM127021NIGMS NIH HHS R35 GM127021
6 · The paper itself

Abstract

Labile low-molecular-mass (LMM) transition metal complexes play essential roles in metal ion trafficking, regulation, and signalling in biological systems, yet their chemical identities remain largely unknown due to their rapid ligand-exchange rates and weak M-L bonds. Here, an Escherichia coli cytosol isolation procedure was developed that was devoid of detergents, strongly coordinating buffers, and EDTA. The interaction of the metal ions from these complexes with a SEC column was minimized by pre-loading the column with

Indexed as

ChromatographyMass SpectrometryCoordination ComplexesCytosolEscherichia coliGene Expression Regulation, BacterialMetalsMolecular WeightCoordination ComplexesMetalsCopperCytosolElectrospray ionization mass spectrometryIronLabile metal poolsManganeseSize-exclusion chromatographyZinc

Identifiers

PMID33963934
PMCPMC8205893
OpenAlexW3157690520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.