Evidence map›Paper›PMID 33963907›Full record

ArticleBioprocess and biosystems engineering2021

Coproduction of polymalic acid and liamocins from two waste by-products from the xylitol and gluconate industries by Aureobasidium pullulans.

Tianfu Li, Wenwen Yang, Xingran Xu, Yan Zhang, Jie Chen, Xiang Zou

Abstract read
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In one paragraph

Article in Bioprocess and biosystems engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. DoE-based medium optimization for improved biosurfactant production withFrontiers in bioengineering and biotechnology · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tianfu LiCollege of Pharmaceutical Sciences, Southwest University, 2 Tian Sheng Road, Beibei, Chongqing, 400715, People's Republic of China.
Wenwen YangCollege of Pharmaceutical Sciences, Southwest University, 2 Tian Sheng Road, Beibei, Chongqing, 400715, People's Republic of China.
Xingran XuCollege of Pharmaceutical Sciences, Southwest University, 2 Tian Sheng Road, Beibei, Chongqing, 400715, People's Republic of China.
Yan ZhangAuhui Sealong Biotechnology Co., Ltd, 6 Jinchong Road, Bengbu, 233316, Anhui Province, People's Republic of China.
Jie ChenSchool of Environmental Ecology and Biological Engineering, Wuhan Institute of Technology, Guanggu 1st road, Wuhan, Hubei Province, 430205, People's Republic of China. algaeoil@126.com.
Xiang ZouCollege of Pharmaceutical Sciences, Southwest University, 2 Tian Sheng Road, Beibei, Chongqing, 400715, People's Republic of China. zhx1030@swu.edu.cn.

Funding

Chongqing Social and People's Livelihood Guarantee Special Program cstc2016shmszx80075Fundamental Research Funds for the Central Universities XDJK2018AC002National High Technology Research and Development Program of China (863 Program) 2015AA021005National Natural Science Foundation of China 31871783 and 31571816
6 · The paper itself

Abstract

The coproduction of polymalic acid (PMA) and liamocins, two important metabolites secreted by Aureobasidium pullulans, from two waste by-products from the xylitol and gluconate industries was investigated in shake flasks and fermentors, confirming that waste xylose mother liquor (WXML) could be utilized as an economical feedstock without any pretreatment. Gluconate could strengthen carbon flux and NADPH supply for the synergetic biosynthesis of PMA and liamocins. High PMA and liamocin titers of 82.9 ± 2.1 and 28.3 ± 2.7 g/L, respectively, were obtained from the coupled WXML and waste gluconate mother liquor (WGML) in batch fermentation, with yields of 0.84 and 0.25 g/g, respectively. These results are comparable to those obtained from renewable feedstocks. Economic assessment of the process revealed that PMA and liamocins could be coproduced from two by-products at costs of $1.48/kg or $0.67/kg (with liamocins credit), offering an economic and sustainable process for the application of waste by-products.

Indexed as

Batch Cell Culture TechniquesMannitolAureobasidiumGluconatesMalatesPolymersXylitolGluconatesgluconic acidMalatesMannitolpoly(malic acid)PolymersXylitolAureobasidium pullulansLiamocinsPolymalic acidWaste gluconate mother liquorWaste xylose mother liquor

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.