Evidence map›Paper›PMID 33963835›Full record

SynthesisEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2021

Driveline exit-site care protocols in patients with left ventricular assist devices: a systematic review.

Zeliha Ozdemir Koken, Yunus C Yalcin, Diana van Netten, Chantal C de Bakker, Maaike van der Graaf, Umit Kervan, Nelianne J Verkaik, Kadir Caliskan

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05163392 (A Silver Lining in the VAD Sky), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05163392 nacompletednot on this mapstarted 2022, after this paper: background citation

A Silver Lining in the VAD Sky: Impact of Silver Dressing on LVAD Associated Driveline Infection

TypeinterventionalSponsorUniversity of California, San FranciscoRan2022 to 2026Enrolled25ConditionsLVAD (Left Ventricular Assist Device) Driveline InfectionArmsSilverlon, Control
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Infections in mechanical circulatory support.Frontiers in cardiovascular medicine · 2026
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Zeliha Ozdemir KokenDepartment of Cardiology, Unit of Heart Failure, Heart Transplantation and Mechanical Circulatory Support, Erasmus University Medical Center, Rotterdam, Netherlands.
Yunus C YalcinDepartment of Cardiology, Unit of Heart Failure, Heart Transplantation and Mechanical Circulatory Support, Erasmus University Medical Center, Rotterdam, Netherlands.ORCID 0000-0002-7358-1518
Diana van NettenDepartment of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, Netherlands.
Chantal C de BakkerDepartment of Cardiology, Unit of Heart Failure, Heart Transplantation and Mechanical Circulatory Support, Erasmus University Medical Center, Rotterdam, Netherlands.
Maaike van der GraafDepartment of Cardiology, Unit of Heart Failure, Heart Transplantation and Mechanical Circulatory Support, Erasmus University Medical Center, Rotterdam, Netherlands.
Umit KervanDepartment of Cardiovascular Surgery, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.ORCID 0000-0001-7198-069X
Nelianne J VerkaikDepartment of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, Netherlands.
Kadir CaliskanDepartment of Cardiology, Unit of Heart Failure, Heart Transplantation and Mechanical Circulatory Support, Erasmus University Medical Center, Rotterdam, Netherlands.ORCID 0000-0002-3293-9261
Erasmus MC · NLSağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDriveline infections continue to be a significant complication following left ventricular assist device (LVAD) implantation. Driveline exit-site care is crucial for the prevention of infections; however, there are no uniform guidelines. The goal of this study was to provide an overview of the currently published driveline exit-site care protocols in patients with LVAD.

methodsA systematic literature review was performed. Studies before 15 December 2020 were included if the number of driveline infections was a primary outcome and the driveline exit-site care protocol was explained.

resultsEleven articles were included in the systematic review, including 1602 patients with LVADs. The median of the frequency of driveline infections in the articles was 13.8% with a range of 0-52.6%. There was a marked variability in the methods of care of driveline exit sites, without a standardized driveline dressing technique in patients with LVADs. The frequency of driveline infections was 6-7.5% in studies using a dressing kit that included chlorhexidine, a silver-based dressing and an anchoring device. Furthermore, there was variability in the anchoring devices and the frequency of dressing changes, which varied from daily to weekly. No specific anchoring device or change frequency was found to be superior.

conclusionsBased on this systematic review, driveline exit care protocols that included chlorhexidine, a silver-based dressing, the use of an anchoring device and dressing kits might be best in reducing driveline infection rates. However, prospective studies with larger cohorts are needed to establish the optimal protocol for driveline exit-site care.

Indexed as

Heart-Assist DevicesHeart FailureProsthesis-Related InfectionsClinical ProtocolsHeart VentriclesHumansProspective StudiesCareDressingDrivelineDriveline infectionLeft ventricular assist deviceProtocols

Identifiers

PMID33963835
PMCPMC8434872
OpenAlexW3157451994

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.