Evidence map›Paper›PMID 33963802›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2021

Evaluation of serum magnesium differences in hypertensive crises and control patients: A randomly matched case-control study.

IfeanyiChukwu O Onor, Emily K Johnston, Nicole G Little, Lashira M Hill, Oluwabunmi E Lawal, Casey J Payne, Mallory R Coleman, Carolkim H Huynh, Sarah E Bilbe, Ahlam A Ayyad and 16 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 4 institutions in 1 country.

IfeanyiChukwu O OnorCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.ORCID 0000-0002-8005-8602
Emily K JohnstonCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Nicole G LittleCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Lashira M HillCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Oluwabunmi E LawalCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Casey J PayneCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Mallory R ColemanCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Carolkim H HuynhCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Sarah E BilbeCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Ahlam A AyyadCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Kabrea J JonesCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Jasmine D KinnardCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Rosanna DastooriCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Devinn K RollandCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Amanda S MillerCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Robbie A BeylPennington Biomedical Research Center, Baton Rouge, LA, USA.
Christopher J GillardCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
John I OkogbaaCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Daniel F SarpongCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Rim M HadguMidwestern University College of Pharmacy - Glendale, Glendale, AZ, USA.
Amne BorgholCardioRenal Research Group (CRRG), College of Pharmacy, Xavier University of Louisiana, New Orleans, LA, USA.
Samuel C OkpechiDepartment of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Mihran V NaljayanDepartment of Medicine, Louisiana State University Health Sciences Center School of Medicine, New Orleans, LA, USA.
Shane E SanneDepartment of Medicine, Louisiana State University Health Sciences Center School of Medicine, New Orleans, LA, USA.
Shane G GuilloryDepartment of Medicine, Louisiana State University Health Sciences Center School of Medicine, New Orleans, LA, USA.
CardioRenal Research Group (CRRG)
Xavier University of Louisiana · USLouisiana State University Health Sciences Center New Orleans · USMidwestern University · USPennington Biomedical Research Center · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Xavier RCMI Renewal Application-Research Infrastructure CoreU54MD007595 · NIMHD · XAVIER UNIVERSITY OF LOUISIANA · PI LaKeisha Williams · 2019 to 2026
$41.9M
Xavier Pharmacy Endowment For Minority HealthS21MD000100 · NIMHD · XAVIER UNIVERSITY OF LOUISIANA · PI FRANCIS, NORMAN C. · 2001 to 2011
$39.0M
Xavier's RCMI Cancer Research ProgramG12MD007595 · NIMHD · XAVIER UNIVERSITY OF LOUISIANA · PI D'AMOUR, GENE, WANG, GUANGDI · 2012 to 2018
$15.7M
HRSA HHS HRSA D34HP00006NIGMS NIH HHS 1 U54 GM104940NIGMS NIH HHS 2U54GM104940-02NIGMS NIH HHS U54 GM104940NIMHD NIH HHS 5 S21 MD 000100-12NIMHD NIH HHS G12 MD007595NIMHD NIH HHS NIH/NIMHD5G12MD007595NIMHD NIH HHS NIMHD 2U54MD007595-11NIMHD NIH HHS S21 MD000100NIMHD NIH HHS U54 MD007595
6 · The paper itself

Abstract

Although the role of magnesium in blood pressure has been well studied among hypertensive patients, no study has explored the role of magnesium in hypertensive crises. The primary objective of this study is to evaluate the differences in serum magnesium levels between hypertensive crises patients and matched controls (age-, sex-, race-, and diabetes-matched) in a 1:1 random match. This study is a single-center, retrospective, chart review, case-control study of patients with hypertensive crises (case group) and patients without hypertensive crises (control group). Patients were included in the case group if they were 18 years of age or older with hypertensive crises and have a documented magnesium level. The control group patients were required to be 18 years of age or older, have no diagnosis of hypertensive crises, and have a documented magnesium level. The primary outcome of the study was to compare the mean serum magnesium in patients with hypertensive crises versus patients without hypertensive crises. Three hundred and fifty-eight patients were included in the study: 179 patients in both the case group and control group. The primary outcome results showed that serum magnesium concentration was not significantly different between the case group (1.89 ± 0.29 mg/dl) and control group (1.90 ± 0.31 mg/dl) (p = .787). This study found no significant difference in serum magnesium levels in patients with hypertensive crises compared to a random matched control group. Larger observational or experimental studies may be useful to evaluate the effect of magnesium on blood pressure in hypertensive crises.

Indexed as

HypertensionMagnesiumAdolescentAdultBlood PressureCase-Control StudiesHumansRetrospective StudiesMagnesiumcalciumhypertensionhypertensive crisesmagnesiumpotassium

Identifiers

PMID33963802
PMCPMC8169553
OpenAlexW3157608398

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.