Evidence map›Paper›PMID 33963787›Full record

ArticleEchocardiography (Mount Kisco, N.Y.)2021

Persistence of abnormal global longitudinal strain in women with peripartum cardiomyopathy.

Anna E Bortnick, Claudia Lama von Buchwald, Aliaskar Hasani, Christina Liu, Julia L Berkowitz, Shayna Vega, Mohammad Hashim Mustehsan, Diana S Wolfe, Cynthia Taub

Abstract read
In one paragraph

Article in Echocardiography (Mount Kisco, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna E BortnickDivision of Cardiology, At Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0001-7983-5243
Claudia Lama von BuchwaldDepartment of Medicine, Division of Cardiology, Rush University Medical Center, Chicago, IL, USA.
Aliaskar HasaniDepartment of Medicine, At Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.
Christina LiuDepartment of Emergency Medicine, Mount Sinai/Morningside West, New York, NY, USA.
Julia L BerkowitzDepartment of Medicine, Brown University Warren Alpert Medical School, Providence, RI, USA.
Shayna VegaDepartment of Obstetrics and Gynecology, Kaiser Permanente Oakland Medical Center, Oakland, CA, USA.
Mohammad Hashim MustehsanDivision of Cardiology, At Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0003-4019-9678
Diana S WolfeMaternal Fetal Medicine-Cardiology Joint Program, At Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.
Cynthia TaubDepartment of Cardiovascular Medicine, Dartmouth-Hitchcock Medical Center and Geisel School of Medicine, Lebanon, NH, USA.

Funding

CTSA Administrative Supplement for Informatics Core: A novel AI/ML system to predict respiratory failure and ARDS in Covid-19 patientsUL1TR002556 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, KIM, MIMI Y · 2018 to 2022
$26.7M
Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
Cardiac Calcification and Cholesterol Efflux in Older AdultsK23HL146982 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BORTNICK, ANNA E · 2020 to 2024
$951k
NCATS NIH HHS UL1 TR001073NCATS NIH HHS UL1 TR002556NHLBI NIH HHS K23 HL146982
6 · The paper itself

Abstract

objectivesData regarding the longitudinal relationship of global longitudinal strain (GLS) and echocardiographic parameters are lacking in peripartum cardiomyopathy (PPCM). We evaluated GLS and its correlation with change (∆) in left ventricular ejection fraction (LVEF).

methodsWe retrospectively identified women age ≥16 years hospitalized at Montefiore Medical Center in Bronx, NY from 1999-2015 with International Statistical Classification of Diseases and Related Health Problems, 9th revision codes for PPCM or an occurrence of unexplained heart failure during or up to 5 months postpartum. N = 195 charts were reviewed for inclusion/exclusion criteria, n = 53 patients met criteria for PPCM, and of those, n = 13 had a baseline and follow-up echocardiogram suitable for GLS analysis.

resultsOf those eligible for strain analysis, the mean age was 30 ± 6 years, 46.2% identified as Black and 38.5% as Hispanic/Latina. Baseline LVEF was 30 (25, 35)%, GLS was -13.2 (-14, -7.6)%. At a mean follow-up time of 1.2 ± 0.7 years, 11/13 had persistently mild -15.6 (-16.3, -12.7)%, and 2/13 severely abnormal GLS -7.05 (-7.1, -7.0)%. There was no correlation between baseline GLS and ∆LVEF (r = .014, P = .965).

conclusionsGlobal longitudinal strain is a sensitive method to identify subclinical myocardial dysfunction. In this series of women with PPCM, GLS remained persistently abnormal over time, even if LVEF improved. Future studies should examine the implication of persistently abnormal GLS in PPCM.

Indexed as

CardiomyopathiesVentricular Dysfunction, LeftAdolescentAdultFemaleHumansPeripartum PeriodRetrospective StudiesStroke VolumeVentricular Function, LeftYoung Adultcardiomyopathyechocardiogramheart failurepregnancy

Identifiers

PMID33963787
PMCPMC8715768

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.