Evidence map›Paper›PMID 33963709›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

[Effect of protein C activator from

Y Sun, P Bao, G Zhang, H Wang, G Wang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Y SunDepartment of Pathophysiology, Wannan Medical College, Wuhu 241002, China.
P BaoInstitute of Snake Venom, Wannan Medical College, Wuhu 241002, China.
G ZhangDepartment of Pathophysiology, Wannan Medical College, Wuhu 241002, China.
H WangInstitute of Snake Venom, Wannan Medical College, Wuhu 241002, China.
G WangSchool of Pharmacy, Wannan Medical College, Wuhu 241002, China.
Wannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of protein C activator (PCA) from

objectiveRat models of sepsis were established by intraperitoneal injection of lipopolysaccharide (LPS; 10 mg/kg) in 36 SD rats, which were divided into 6 groups (

objectiveThe plasma levels of S1P, IL-12, IL-4 and IFN-γ (

objectivePCA can regulate the balance of inflammation and immune response in the early stage of sepsis in rats possibly through the S1P-S1PR1 pathway.

Indexed as

AgkistrodonSepsisAdaptive ImmunityAnimalsProtein CRatsRats, Sprague-DawleyVenomsProtein CVenomsadaptive immune responseAgkistrodon acutus venomprotein C activatorsepsissphingosine-1-phosphatesphingosine-1-phosphate receptor 1

Identifiers

PMID33963709
PMCPMC8110449
OpenAlexW3159887052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.