Evidence map›Paper›PMID 33963706›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

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B Bao, J Liu, L Wan, Y Zhang, Y Long, G Sun

Open access · greenAbstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Complement 3 and 4 impact in osteoarthritis.Biomarkers in medicine · 2025
    Article
  3. Article
  4. Article
  5. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

B BaoFirst Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
J LiuFirst Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
L WanFirst Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
Y ZhangFirst Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
Y LongFirst Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
G SunFirst Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
Anhui University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo observe the inhibitory effect of

objectiveThirty OA patients and 30 healthy subjects were examined for the expression of miR-23a-3p/PTEN/PI3K/AKT/mTOR. The changes in the miR-23a-3p/ PTEN/PI3K/AKT/mTOR pathway and the clinical indicators of the OA patients after XFC treatment were observed. OA-CD4

objectiveCompared with healthy individuals, OA patients showed significantly increased expressions of miR-23a-3p, PTEN, PI3K, AKT, IL-1β, IL-6 and TNF-α and lowered expressions of PTEN and IL-10 (

objectiveXFC can reduce the inflammatory response in patients with OA by down-regulating the expression of miR-23a-3p, inhibiting the activation of the PTEN/PI3K/AKT/ mTOR pathway, and regulating the expression of IL-1β, IL-6, IL-10 and TNF-α.

Indexed as

MicroRNAsOsteoarthritisApoptosisDrugs, Chinese HerbalHumansInflammationPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesDrugs, Chinese HerbalMicroRNAsMTOR protein, humanPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine Kinasesxinfengimmuno-inflammatory responsesmiR-23a-3posteoarthritisPTEN/PI3K/AKT/mTORXinfeng capsule

Identifiers

PMID33963706
PMCPMC8110458
OpenAlexW3157838420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.