Evidence map›Paper›PMID 33963454›Full record

ArticleMagma (New York, N.Y.)2021

Comparison of 2D and 3D quiescent-interval slice-selective non-contrast MR angiography in patients with peripheral artery disease.

Akos Varga-Szemes, Pascale Aouad, U Joseph Schoepf, Tilman Emrich, Basel Yacoub, Thomas M Todoran, Ioannis Koktzoglou, Robert R Edelman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Akos Varga-SzemesDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, MSC 226, Charleston, SC, 29425, USA. vargaasz@musc.edu.ORCID http://orcid.org/0000-0002-2781-7462
Pascale AouadDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
U Joseph SchoepfDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, MSC 226, Charleston, SC, 29425, USA.
Tilman EmrichDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, MSC 226, Charleston, SC, 29425, USA.
Basel YacoubDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, MSC 226, Charleston, SC, 29425, USA.
Thomas M TodoranDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA.
Ioannis KoktzoglouDepartment of Radiology, Northshore University HealthSystem, Evanston, IL, USA.
Robert R EdelmanDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Medical University of South Carolina · USNorthwestern University · USNorthShore University HealthSystem · US

Funding

Nonenhanced 3T QISS MR Angiography of the Peripheral ArteriesR01HL130093 · NHLBI · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI EDELMAN, ROBERT R. · 2016 to 2019
$2.0M
Projection Imaging of Peripheral Vascular CalcificationsR21HL126015 · NHLBI · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI EDELMAN, ROBERT R. · 2015 to 2016
$442k
NHLBI NIH HHS R01 HL130093NHLBI NIH HHS R21 HL126015
6 · The paper itself

Abstract

objectiveTo evaluate the potential clinical benefit of the superior spatial resolution of 3D prototype thin-slab stack-of-stars (tsSOS) quiescent-interval slice-selective (QISS) MRA over standard 2D-QISS MRA for the detection peripheral artery disease (PAD), using computed tomography angiography (CTA) as reference. MATERIALS AND

methodsTwenty-three patients (70 ± 8 years, 18 men) with PAD who had previously undergone run-off CTA were prospectively enrolled. Patients underwent non-contrast MRA using 2D-QISS and tsSOS-QISS at 1.5 T. Eighteen arterial segments were evaluated for subjective and objective image quality (normalized signal-to-noise, nSNR), vessel sharpness, and area under the curve (AUC) for > 50% stenosis detection.

resultsOverall subjective image quality ratings for the entire run-off were not different between tsSOS-QISS and 2D-QISS (3 [3; 4] vs 4 [3; 4], respectively; P = 0.813). Sharpness of primary branch vessels demonstrated improved image quality using tsSOS-QISS compared with 2D-QISS (4 [3; 4] vs 3 [2; 3], P = 0.008). Objective image quality measures were not different between 2D-QISS and tsSOS-QISS (nSNR 5.0 ± 1.9 vs 4.2 ± 1.8; P = 0.132). AUCs for significant stenosis detection by tsSOS-QISS and 2D-QISS were 0.877 and 0.856, respectively (P = 0.336). DISCUSSION: The prototype 3D tsSOS-QISS technique provides similar accuracy in patients with PAD to a standard commercially available 2D-QISS technique, indicating that the use of relatively thick slices does not limit the diagnostic performance of 2D-QISS. However, subjective image quality for branch vessel depiction is improved using the 3D approach.

Indexed as

Peripheral Arterial DiseaseConstriction, PathologicContrast MediaHumansMagnetic Resonance AngiographyMaleReproducibility of ResultsContrast MediaComputed tomography angiographyMagnetic resonance angiographyPeripheral arterial disease

Identifiers

PMID33963454
PMCPMC12599201
OpenAlexW3158675747

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.